Privigen
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Gammagard Liquid
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Summary for Privigen
Privigen is an immunoglobulin (antibody) therapy known as intravenous immunoglobulin (IVIG). It's used to treat certain immune-related conditions like primary humoral immunodeficiency (PI), chronic immune thrombocytopenic purpura) (ITP), and chronic inflammatory demyelinating polyneuropathy (CIDP). It’s given by infusion into a vein (IV), typically in a clinic or infusion center. Common side effects include headache, nausea, and tiredness.
Indications for Privigen
- Primary humoral immunodeficiency (PI) - adults and children 3 years and older
- To raise platelet counts in people with immune thrombocytopenia (ITP) - adults and teens 15 years and older
- Chronic inflammatory demyelinating polyneuropathy (CIDP) - adults
Pros and Cons for Privigen
Pros
- Approved to treat PI, ITP, and CIDP
- Flexible dosing schedules for different conditions
- Could be given at home by trained healthcare professionals in some cases
Cons
- Requires IV access and monitored infusions
- Risk of blood clots and kidney problems
- Can interfere with live vaccines
- Headache, nausea, and flu-like symptoms are common after infusions
Common Side Effects for Privigen
PI
- Headache (45%)
- Fatigue (16%)
- Nausea (14%)
- Chills (11%)
- Vomiting (11%)
- Back pain (10%)
- Pain (9%)
- Fever (9%)
- Diarrhea (8%)
ITP
- Headache (65%)
- Fever (37%)
- Low red blood cells (11%)
- Nausea (11%)
- Nosebleed (11%)
- Vomiting (11%)
CIDP
- Headache (29%)
- Low energy (14%)
- High blood pressure (14%)
- Nausea (11%)
- Pain in arms or legs (11%)
Warnings for Privigen
- Kidney failure
- Blood clots
- Serious allergic reactions
- High protein levels, thick blood, and low sodium
- Swelling in the brain
- Breakdown of red blood cells
- High blood pressure
- Serious lung problem
- Risk of infection
Summary for Gammagard Liquid
Gammagard Liquid is an immunoglobulin (antibody) infusion known as intravenous immunoglobulin (IVIG). It treats certain immune-related conditions, including primary immunodeficiency (PI), multifocal motor neuropathy (MMN), and chronic inflammatory demyelinating polyneuropathy (CIDP). Gammagard Liquid is typically infused through the vein, but can also be given as an infusion under the skin for PI. How often you receive a dose differs depending on your condition, but can range from weekly to every 4 weeks. Gammagard Liquid can raise your risk of serious side effects, including blood clots and kidney problems.
Indications for Gammagard Liquid
- Primary humoral immunodeficiency or PI in adults and children ages 2 years and older
- Multifocal motor neuropathy (MMN) in adults
- Chronic inflammatory demyelinating polyneuropathy (CIDP) in adults
Pros and Cons for Gammagard Liquid
Pros
- Can be given as IV or SQ infusion for PI
- Can be given at home, if your prescriber approves
- Conveniently stored at room temperature or in the refrigerator
Cons
- Infusion site reactions, like swelling or redness, are very common for under-the-skin injections.
- Has a lot of potential risks, such as kidney and lung problems
- Requires occasional blood tests to check for side effects and the need for dose adjustments
Common Side Effects for Gammagard Liquid
Primary humoral immunodeficiency (IV infusion):
- Headache (48%)
- Feeling tired (23%)
- Fever (28%)
- Nausea (18%)
- Diarrhea (15%)
- Vomiting (15%)
- Cough (13%)
- Chills (13%)
- Dizziness (13%)
- Pain in arms or legs (12%)
Multifocal motor neuropathy:
- Headache (32%)
Chronic inflammatory demyelinating polyneuropathy:
- Headache (40%)
- Fever (10%)
Warnings for Gammagard Liquid
- Risk of blood clots
- Kidney problems
- Serious allergic reactions
- Inflammation of the brain
- Anemia due to breakdown of red blood cells
- Spread of local infection
- Lung problems
- Risk of infection
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