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Compare Otulfi vs. Stelara

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Otulfi (ustekinumab)
    Stelara (ustekinumab)
  • Otulfi (ustekinumab)
    Stelara (ustekinumab)

  • Summary of Otulfi vs. Stelara

    Summary for IL-12 and IL-23 antagonist
    Prescription only

    Otulfi (ustekinumab or ustekinumab-aauz) is a biologic medication and a biosimilar to Stelara (ustekinumab). Like Stelara (ustekinumab), it's FDA approved to treat several autoimmune conditions, such as plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. It works by lowering inflammation through blocking proteins in the body called interleukins. The medication is typically given as an injection under the skin, with doses spaced every 8 to 12 weeks based on your condition. Common side effects include tiredness, headache, and cold-like symptoms.

    Summary for IL-12 and IL-23 antagonist
    Prescription only

    Stelara (ustekinumab) is an injectable medication used to treat autoimmune conditions like plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. As an interleukin antagonist, it works by blocking certain proteins that cause inflammation in your body, which helps reduce swelling and ease symptoms. You typically get it as an injection under your skin. Common side effects include common cold symptoms, headache, and feeling tired. This medication also has many biosimilars available.

  • Indications of Otulfi vs. Stelara

    Indications for
    •Moderate-to-severe plaque psoriasis (Ps) - adults and children 6 years and older
    •Psoriatic arthritis (PsA) - adults and children 6 years and older
    •Moderate-to-severe Crohn's disease (CD) - adults only
    •Moderate-to-severe ulcerative colitis (UC) - adults only
    Indications for
    •Moderate-to-severe plaque psoriasis (Ps) - adults and children 6 years and older
    •Psoriatic arthritis (PsA) - adults and children 6 years and older
    •Moderate-to-severe Crohn's disease (CD) - adults only
    •Moderate-to-severe ulcerative colitis (UC) - adults only

  • Pros and Cons of Otulfi vs. Stelara

    Pros and Const for IL-12 and IL-23 antagonist
    Pros
    •Biosimilar that's interchangeable with Stelara (ustekinumab)
    •Syringes can be stored at room temperature for up to 30 days
    •Approved for children as young as 6 years old for certain conditions
    •Stopper isn't made of natural rubber latex
    Cons
    •Can weaken your immune system and raise your risk of infection
    •Potential to cause serious allergic reactions
    •For CD and UC, the first dose must be given as an IV infusion
    •Can't receive live vaccines while taking this medication
    Pros and Const for IL-12 and IL-23 antagonist
    Pros
    •After the first few doses, only need a shot every 8 to 12 weeks
    •Available as a prefilled syringe or vial
    •Syringes can be stored at room temperature for up to 30 days
    •Approved for children as young as 6 years old
    Cons
    •Can weaken your immune system and raise your risk of infection
    •Potential to cause serious allergic reactions
    •For CD and UC, the first dose must be given as an IV infusion
    •Can't receive live vaccines while taking this medication

  • Common Side Effects of Otulfi vs. Stelara

    Common Side Effects for

    Plaque psoriasis

    •Common cold symptoms (7-8%)
    •Upper respiratory tract infection (4-5%)
    •Headache (5%)

    Psoriatic arthritis

    •Joint pain (3%)
    •Nausea (3%)

    Crohn's disease

    •Common cold symptoms (11%)
    •Redness at the injection site (5%)
    •Yeast infection (5%)
    •Bronchitis (5%)

    Ulcerative colitis:

    •Common cold symptoms (24%)
    •Headache (10%)
    •Stomach pain (7%)
    •Flu infection (6%)
    •Fever (5%)
    Common Side Effects for

    Plaque psoriasis

    •Common cold symptoms (7-8%)
    •Upper respiratory tract infection (4-5%)
    •Headache (5%)

    Psoriatic arthritis

    •Joint pain (3%)
    •Nausea (3%)

    Crohn's disease

    •Common cold symptoms (11%)
    •Redness at the injection site (5%)
    •Yeast infection (5%)
    •Bronchitis (5%)

    Ulcerative colitis:

    •Common cold symptoms (24%)
    •Headache (10%)
    •Stomach pain (7%)
    •Flu infection (6%)
    •Fever (5%)

  • Warnings of Otulfi vs. Stelara

    Common Side Effects for
    •Infections
    •Cancers
    •Severe allergic reaction
    •Brain condition
    •Vaccines
    •Lung problems
    Common Side Effects for
    •Infections
    •Cancers
    •Severe allergic reaction
    •Brain condition
    •Vaccines
    •Lung problems

  • Prices with our coupons for Otulfi vs. Stelara

    Learn more about Otulfi
    Learn more about Stelara

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