Mirabegron vs. Ditropan XL for Overactive Bladder: Important Differences and Potential Risks.

Myrbetriq

(mirabegron)

Oxybutynin

Summary for Mirabegron

Prescription only

Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

Indications for Mirabegron

Overactive bladder (OAB) in adults
Neurogenic detrusor overactivity (NDO) in children ages 3 years and older

Pros and Cons for Mirabegron

Pros

Helps control sudden urges to urinate, leaks, and needing to go too often
Only taken once a day
Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
Might be safer for older adults than anticholinergics for overactive bladder

Cons

Might raise your blood pressure
Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
Not recommended if you have severe kidney or liver problems

Common Side Effects for Mirabegron

Adults:

High blood pressure (8-11%)
Common cold symptoms (4%)
Urinary tract infection (3-4%)
Headache (2-3%)
Constipation (2%)
Upper respiratory tract infection (2%)

Children:

Urinary tract infection (24%)
Common cold symptoms (6%)
Constipation (5%)
Headache (4%)
Nausea (2%)

Warnings for Mirabegron

High blood pressure
Risk of having trouble fully emptying the bladder in certain people
Unusual swelling of the face, lips, or throat (angioedema)
Interactions with other medications

Summary for Ditropan XL

Prescription only

Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

Indications for Ditropan XL

Overactive bladder
Incontinence in children due to a neurologic (brain) condition, such as spina bifida

Pros and Cons for Ditropan XL

Pros

Works well to improve symptoms of OAB
Available as a convenient, once-daily tablet (Ditropan XL)
Can be used in children as young as 5 years old
Available as an oral liquid, good for people who have trouble swallowing tablets

Cons

Commonly causes dry mouth as a side effect
Higher risk of side effects in people age 65 and older
Can cause dizziness and drowsiness
Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines

Common Side Effects for Ditropan XL

Dry mouth (up to 71%)
Dizziness (up to 17%)
Constipation (up to 15%)
Sleepiness (up to 14%)
Nausea (up to 12%)
Blurry vision (up to 10%)

Warnings for Ditropan XL

Swelling of face, lips, tongue (angioedema)
Hallucinations, drowsiness, and confusion
Worsening of other conditions
Heat exhaustion

Prices with our coupons for Mirabegron vs. Ditropan XL

Mirabegron30 tablets / 50mg

$121.10$242.50

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Oxybutynin ER30 tablets / 10mg

$8.50$68.75

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Mirabegron vs. Ditropan XL

Myrbetriq

Oxybutynin

Summary for Mirabegron

Indications for Mirabegron

Pros and Cons for Mirabegron

Pros

Cons

Common Side Effects for Mirabegron

Warnings for Mirabegron

Summary for Ditropan XL

Indications for Ditropan XL

Pros and Cons for Ditropan XL

Pros

Cons

Common Side Effects for Ditropan XL

Warnings for Ditropan XL

Prices with our coupons for Mirabegron vs. Ditropan XL

Browse medications by letter

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Myrbetriq

Oxybutynin

Summary for Mirabegron

Indications for Mirabegron

Pros and Cons for Mirabegron

Pros

Cons

Common Side Effects for Mirabegron

Warnings for Mirabegron

Summary for Ditropan XL

Indications for Ditropan XL

Pros and Cons for Ditropan XL

Pros

Cons

Common Side Effects for Ditropan XL

Warnings for Ditropan XL