Lumvoa vs. Tepezza for Thyroid Eye Disease: Important Differences and Potential Risks.

Lumvoa

(veligrotug)

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Tepezza

(teprotumumab)

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Summary for Lumvoa

Prescription only

Lumvoa (veligrotug or veligrotug-vyze) is a medication that treats thyroid eye disease in adults. It works as an insulin-like growth factor-1 receptor inhibitor to help with symptoms like eye discomfort and swelling. Lumvoa (veligrotug) is given as an intravenous (IV) infusion into a vein every 3 weeks by a healthcare professional. Full treatment is a total of 5 infusions. Common side effects include muscle spasms, headaches, ear discomfort, and infusion reactions.

Indications for Lumvoa

Thyroid eye disease

Pros and Cons for Lumvoa

Pros

Given every 3 weeks
Only need a total of 5 doses for full treatment
Can reduce swelling of the eyes and vision changes

Cons

Given as an infusion into a vein in the arm, which can be inconvenient
May cause muscle spasms
May cause changes in hearing, including hearing loss

Common Side Effects for Lumvoa

Muscle spasms (40%)
Unusual menstrual patterns (irregular or lack of periods, severe cramping, bleeding between periods; 29%)
Headache (17%)
Hearing difficulties (ringing in the ears, trouble hearing; 15%)
High blood sugar (13%)
Fatigue (13%)
Diarrhea (11%)
Ear discomfort (ear pressure, clogged ear, ear popping; 10%)

Warnings for Lumvoa

Infusion reactions
Inflammatory bowel disease (IBD) flare-up
High blood sugar
Hearing difficulties, including hearing loss
Risk of harm to a developing baby during pregnancy

Summary for Tepezza

Prescription only

Tepezza (teprotumumab-trbw or teprotumumab) treats a rare condition called thyroid eye disease (TED), sometimes known as Graves’ orbitopathy. It's the only medication FDA-approved for the treatment of TED and works well to reduce eye bulging, pain, and redness. Tepezza (teprotumumab) is given as an infusion into the veins by a healthcare provider. The full treatment only requires 8 doses, each dose given 3 weeks apart. Tepezza (teprotumumab) can cause common side effects such as nausea and muscle spasms. It also can cause infusion-related reactions such as feeling hot, headache, or trouble breathing.

Indications for Tepezza

Thyroid eye disease

Pros and Cons for Tepezza

Pros

The only medication FDA-approved for people with TED
Can reduce how much your eye bulges out and improve your double vision
Only need 8 total infusions for a full treatment course

Cons

Can cause infusion-related reaction (e.g., feeling hot, headache, or trouble breathing)
Given IV, so it’s not as convenient as taking a pill
Only available as a brand name medication, so it can be expensive

Common Side Effects for Tepezza

Muscle spasms (25%)
Nausea (17%)
Hair loss (13%)
Diarrhea (12%)
Tiredness (12%)
Higher blood sugar levels (10%)
Trouble hearing (10%)

Warnings for Tepezza

Infusion-related reactions
Inflammation of the gastrointestinal tract
High blood sugars

Prices with our coupons for Lumvoa vs. Tepezza

Lumvoa2 vials / 10ml of 500mg/10ml

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Tepezza3 vials / 500mg of

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Lumvoa vs. Tepezza

Lumvoa

Tepezza

Summary for Lumvoa

Indications for Lumvoa

Pros and Cons for Lumvoa

Pros

Cons

Common Side Effects for Lumvoa

Warnings for Lumvoa

Summary for Tepezza

Indications for Tepezza

Pros and Cons for Tepezza

Pros

Cons

Common Side Effects for Tepezza

Warnings for Tepezza

Prices with our coupons for Lumvoa vs. Tepezza

Browse medications by letter

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Lumvoa

Tepezza

Summary for Lumvoa

Indications for Lumvoa

Pros and Cons for Lumvoa

Pros

Cons

Common Side Effects for Lumvoa

Warnings for Lumvoa

Summary for Tepezza

Indications for Tepezza

Pros and Cons for Tepezza

Pros

Cons

Common Side Effects for Tepezza

Warnings for Tepezza