Heplisav-B vs. Engerix-B for Hepatitis B: Important Differences and Potential Risks.

Heplisav-B

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Hepatitis B vaccine

(Recombivax HB)

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Summary for Heplisav-B

Prescription only

Heplisav-B is a vaccine that helps protect against hepatitis B infection from the hepatitis B virus. It's approved for adults ages 18 years and older. Heplisav-B is given as an injection into the shoulder muscle by a healthcare professional. The complete vaccine series is 2 doses given a month apart. Common side effects are pain at the injection site and tiredness.

Indications for Heplisav-B

Prevention of hepatitis B in adults

Pros and Cons for Heplisav-B

Pros

Only requires 2 doses given 1 month apart
Can be given at the same visit with other vaccines

Cons

Approved only for adults 18 years and older
Can cause pain where the vaccine is given

Common Side Effects for Heplisav-B

Pain at injection site
Tiredness
Headache

Warnings for Heplisav-B

Allergic reaction
Weaker immune response in people with a weak immune system

Summary for Engerix-B

Prescription only

Hepatitis B vaccine (Recombivax HB) is a vaccine used to lower your risk of getting a hepatitis B infection from the hepatitis B virus. It's given as an injection into the muscle. Hepatitis B vaccine (Recombivax HB) is a routine vaccine for all babies, but it can also be given to children and adults.

Indications for Engerix-B

Prevention of hepatitis B

Pros and Cons for Engerix-B

Pros

Can be given with other vaccines
Can receive either brand name (Recombivax HB or Engerix-B), regardless of previous brand received
Protection lasts for at least 30 years in healthy people who received hepatitis B vaccine (Recombivax HB) at at least 6 months of age.

Cons

Recombivax HB and Engerix-B both contain latex, which can be a problem for people with latex allergies.
Only given as an injection into the muscle
Must be given by a healthcare professional at a provider’s office, clinic, or pharmacy

Common Side Effects for Engerix-B

Recombivax HB (at least 1%):

Feeling irritated
Fever
Diarrhea
Fatigue/weakness
Poor appetite
Nasal symptoms (runny nose, congestion, sneezing, itching)

Engerix-B

Soreness at injection site (22%)
Fatigue (14%)
Dizziness (1-10%)
Headache (1-10%)
Fever (1-10%)

Warnings for Engerix-B

Severe allergic reactions
Breathing issues (apnea) in premature babies
Low birth weight
Lower response to hepatitis B vaccine (Recombivax HB)
Fainting

Prices with our coupons for Heplisav-B vs. Engerix-B

Heplisav-B1 syringe / 0.5ml

$156.08$249.98

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Engerix-B1 syringe / 1ml of 20mcg/ml

$84.47$109.58

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Heplisav-B vs. Engerix-B

Heplisav-B

Hepatitis B vaccine

Summary for Heplisav-B

Indications for Heplisav-B

Pros and Cons for Heplisav-B

Pros

Cons

Common Side Effects for Heplisav-B

Warnings for Heplisav-B

Summary for Engerix-B

Indications for Engerix-B

Pros and Cons for Engerix-B

Pros

Cons

Common Side Effects for Engerix-B

Warnings for Engerix-B

Prices with our coupons for Heplisav-B vs. Engerix-B

Browse medications by letter

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Heplisav-B

Hepatitis B vaccine

Summary for Heplisav-B

Indications for Heplisav-B

Pros and Cons for Heplisav-B

Pros

Cons

Common Side Effects for Heplisav-B

Warnings for Heplisav-B

Summary for Engerix-B

Indications for Engerix-B

Pros and Cons for Engerix-B

Pros

Cons

Common Side Effects for Engerix-B

Warnings for Engerix-B