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Fluoxymesterone vs. Testopel

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Androxy (fluoxymesterone) and Testopel (testosterone) are both used to treat low testosterone in males, but they have some key differences. Androxy, an androgen, was available in oral form and also used to treat breast cancer in females, but it has been discontinued in the United States. On the other hand, Testopel is a testosterone replacement therapy available as an implantable pellet, which is placed under the skin by a healthcare provider. Testopel is long-acting, requiring implantation every 3 to 6 months, whereas Androxy was taken orally. Additionally, Testopel is not recommended for men with breast or prostate cancer, while Androxy was used to slow the spread of metastatic breast cancer in females. Testopel also has specific risks related to the implantation procedure, such as infection and pellet extrusion, which are not concerns with the discontinued oral Androxy.

Androxy

(fluoxymesterone)

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Testopel

(testosterone pellets)

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Summary for Fluoxymesterone

Discontinued

Androxy (fluoxymesterone) is a medication used for treating conditions caused by low testosterone in males. It is also used to treat breast cancer in females. Androxy (fluoxymesterone) is no longer available in the United States because it was discontinued.

Pros and Cons for Fluoxymesterone

Pros

Cons

Summary for Testopel

Prescription only

Testopel (testosterone pellets) is an implantable pellet medication used as long-acting testosterone replacement therapy. It treats certain males with low testosterone and delayed puberty. The pellets are implanted, or placed under your skin, by a healthcare professional (HCP) typically every 3 to 6 months. Side effects include pain and swelling at the implantation site, as well as sexual side effects like more frequent erections and changes in sex drive.

Indications for Testopel

Pros and Cons for Testopel

Pros

  • A long-acting testosterone replacement medication
  • Implanted every 3 to 6 months
  • Can be used in children and adults
  • Unlike testosterone gel, there’s no risk of accidentally exposing others to testosterone

Cons

  • Can cause pain and swelling at the implantation site
  • Risk of infections or extrusions at the implantation site
  • Is a surgical procedure that must be done at the prescriber's office
  • Dose adjustments are difficult since they require surgical removal or addition of pellets

Common Side Effects for Testopel

  • Enlargement of male breasts
  • Pain or swelling at the implantation site

Warnings for Testopel

  • Infection and extrusion at the implantation site
  • Risk of blood clots, including heart attack or stroke
  • Potential for misuse, dependency, and addiction
  • Prostate problems
  • Liver problems
  • Swelling in the legs or arms (edema)
  • High calcium in the blood
  • Sexual side effects
  • Fast bone maturation in children

Prices with our coupons for Fluoxymesterone vs. Testopel

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Androxy30 tablets / 10mg
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Testopel1 box / 10 pellets of 75mg
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