Key takeaways
Androxy (fluoxymesterone) and Axiron (testosterone) are both medications used to treat low testosterone in males, but they have significant differences. Androxy, an oral androgen, has been discontinued and is no longer available in the United States. It was also used to treat breast cancer in females. On the other hand, Axiron is a topical testosterone replacement applied to the armpits and is still available in a generic form. Axiron is convenient because it only needs to be applied once a day and has a lower risk of transferring testosterone to others compared to gels. However, it requires careful application to avoid accidental exposure and has several potential side effects, including heart attack, stroke, and blood clots. Unlike Androxy, Axiron can also lower sperm count, especially in larger doses, affecting fertility. Both medications are controlled substances due to their potential for abuse and dependence.
