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Fluoxymesterone vs. Androderm

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Androxy (fluoxymesterone) and Androderm (testosterone patch) are both testosterone replacement therapies, but they have some key differences. Androxy, which is taken orally, was used to treat low testosterone in males and breast cancer in females. However, it has been discontinued and is no longer available in the United States. On the other hand, Androderm is a transdermal patch applied to the skin once a day to treat low testosterone in adult males. Androderm has also been discontinued in the U.S. Both medications are Schedule III controlled substances due to their potential for abuse and dependence. Androderm can cause skin irritation at the application site, while Androxy, being an oral medication, does not have this issue. If you need testosterone replacement therapy, you should talk to your healthcare provider about alternative options.

Androxy

(fluoxymesterone)

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Androderm

(testosterone patch)

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Summary for Fluoxymesterone

Discontinued

Androxy (fluoxymesterone) is a medication used for treating conditions caused by low testosterone in males. It is also used to treat breast cancer in females. Androxy (fluoxymesterone) is no longer available in the United States because it was discontinued.

Pros and Cons for Fluoxymesterone

Pros

Cons

Summary for Androderm

Prescription only

Androderm (testosterone patch) is a testosterone replacement therapy that acts like the natural sex hormone testosterone. It raises testosterone levels in adult males who are diagnosed with low testosterone, also known as hypogonadism. Androderm (testosterone patch) is a patch that's applied to your skin once a day. Some common effects of this medication include skin irritation, itching, and burning.

Please note: Androderm (testosterone patch) has been discontinued and is no longer available in the United States. Talk to your primary care provider about alternative testosterone replacement therapies available to treat low testosterone.

Indications for Androderm

Pros and Cons for Androderm

Pros

  • Compared to testosterone gel, there’s a lower risk of accidentally exposing others to testosterone
  • Doesn't need to be removed during sex or while showering or bathing
  • Applied to your skin
  • Applied once a day

Cons

  • Can cause skin irritation
  • Need to remember to rotate application sites every night
  • Heavy exercise or sweating too much might cause the patch to loosen or fall off
  • Need to wait 3 hours before you can shower, swim, or bathe

Common Side Effects for Androderm

  • Application site itchiness (17%)
  • Application site blisters (6%)
  • Back pain (6%)

Warnings for Androderm

  • Higher red blood cell count and high risk of heart attack or stroke
  • Blood clots
  • Potential for misuse, dependency, and addiction
  • Worsening symptoms of enlarged prostate and prostate cancer
  • Liver problems
  • Low sperm count
  • Swelling in the legs or arms (edema)
  • Breathing problems during sleep (sleep apnea)
  • High calcium in the blood

Prices with our coupons for Fluoxymesterone vs. Androderm

Price Card Drug Icon
Androxy30 tablets / 10mg
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Androderm1 carton / 60 patches of 2mg per day
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