Evrysdi
(risdiplam)
Get free couponsSpinraza
(nusinersen)
Get free couponsSummary for Evrysdi
Evrysdi (risdiplam) is used to treat a genetic condition called spinal muscular atrophy (SMA) in adults and children. It's a type of medication called an RNA splicing modifier. It works to help improve the motor function of people with SMA. Evrysdi (risdiplam) comes as a tablet and oral solution, and you take the medication by mouth once per day. But your specific dose depends on your age and weight. Side effects can include fever, diarrhea, and rash.
Indications for Evrysdi
- Spinal muscular atrophy (SMA) in adults and children
Pros and Cons for Evrysdi
Pros
- Taken by mouth once a day
- Okay for people of all ages with SMA to take
- Available as a tablet and a liquid
Cons
- Can cause diarrhea
- Must follow a lot of instructions to take the liquid safely (e.g., refrigeration, no mixing with food)
- Can take months to notice better muscle strength
Common Side Effects for Evrysdi
- Fever (22%)
- Diarrhea (17%)
- Rash (17%)
Warnings for Evrysdi
- Possible interactions with other medications
- Possible harm to an unborn baby
- Possible fertility problems in males
Summary for Spinraza
Spinraza (nusinersen) is an injectable medication used to treat spinal muscular atrophy (SMA) in children and adults. This medication is injected into the spinal canal by a trained healthcare provider at a treatment facility.
Indications for Spinraza
- Treatment of spinal muscular atrophy (SMA) in children and adults
Pros and Cons for Spinraza
Pros
- Can be given to both children and adults of all ages
- Maintenance dose only has to be given every 4 months
- Medication gets injected directly into the spinal area, where movement is controlled
Cons
- Must be given by injection, so it might be uncomfortable
- Only given by a trained healthcare provider
- Must complete blood work and urine test before each dose
Common Side Effects for Spinraza
Infantile-onset SMA (affects infants)
- Lower respiratory infection (55%)
- Constipation (35%)
- Teething (18%)
- Urinary tract infection (9%)
- Stuffy nose (8%)
- Ear infection (6%)
- Passing gas (5%)
- Weight loss (5%)
Later-onset SMA (affects children and adults)
- Fever (43%)
- Headache (29%)
- Vomiting (29%)
- Back pain (25%)
- Nosebleed (7%)
- Falls (5%)
- Stuffy nose (5%)
- Seasonal allergy (5%)
Warnings for Spinraza
- Bleeding risk
- Kidney damage
Prices with our coupons for Evrysdi vs. Spinraza
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