Crinone vs. Prometrium for Irregular Menstruation: Important Differences and Potential Risks.

Crinone

(progesterone)

Progesterone

(Prometrium)

Summary for Crinone

Prescription only

Crinone (progesterone) is a vaginal gel that's used in fertility treatments. It's also used to help restart menstrual periods. This medication contains progesterone, which is a hormone that's naturally made in the body. You insert Crinone (progesterone) into the vagina using a prefilled applicator. For fertility, it's inserted once or twice a day. And for menstrual periods, the medication is inserted every other day. Some possible side effects include headache, stomach pain, and vaginal discharge.

Indications for Crinone

Infertility
Lack of menstrual periods

Pros and Cons for Crinone

Pros

Comes with easy-to-use, prefilled applicators
Used less often than the alternative progesterone vaginal insert
Not as painful as progesterone injections

Cons

Might cause breast growth and breast pain
Might be uncomfortable to use for some
Can cause messy discharge, so you might need to wear panty liners
Not available as a lower-cost generic

Common Side Effects for Crinone

Breast growth (40%)
Sleepiness (27%)
Constipation (27%)
Nausea (22%)
Headache (17%)
Pain around the vaginal opening (17%)
Nervousness (16%)
Needing to urinate in the middle of the night (13%)
Stomach pain (12%)
Depression (11%)
Lowered sex drive (10%)

Warnings for Crinone

Blood clots
Not FDA-approved for preventing miscarriage
Fluid buildup
Worsening depression
Possible rise in blood sugar levels

Summary for Prometrium

Prescription only

Progesterone (Prometrium) is an oral medication used to protect the uterus in postmenopausal women (those who've gone through menopause) who are also taking estrogen. It can also help regulate menstrual cycles in people who aren't getting their period. The medication is typically taken by mouth once at bedtime for 10-12 days, depending on what you're taking it for. Potential side effects include headache, weight gain or weight loss, and breast tenderness.

Indications for Prometrium

Protection of the uterus for postmenopausal women also taking estrogen medications
Lack of menstrual periods due to hormone imbalance

Pros and Cons for Prometrium

Pros

Helps protect the uterus and regulate periods
Taken by mouth once a day
Might be easier to take than the injection form

Cons

Not a good option for people with liver problems
Shouldn't be used in people with a peanut allergy
Potentially raises your risk of serious blood clots

Common Side Effects for Prometrium

Headache (31%)
Breast tenderness (27%)
Joint pain (20%)
Depression (19%)
Dizziness (15%)
Stomach bloating (12%)
Hot flashes (11%)
Trouble urinating (11%)
Stomach pain (10%)
Vaginal discharge (10%)

Warnings for Prometrium

Blood clots
Breast cancer
Dementia
Vision problems
Dizziness and drowsiness
Fluid buildup

Prices with our coupons for Crinone vs. Prometrium

Crinone15 applicators / 1.45g of 8%

$480.63$555.45

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Progesterone30 capsules / 100mg

$16.25$121.82

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Crinone vs. Prometrium

Crinone

Progesterone

Summary for Crinone

Indications for Crinone

Pros and Cons for Crinone

Pros

Cons

Common Side Effects for Crinone

Warnings for Crinone

Summary for Prometrium

Indications for Prometrium

Pros and Cons for Prometrium

Pros

Cons

Common Side Effects for Prometrium

Warnings for Prometrium

Prices with our coupons for Crinone vs. Prometrium

Browse medications by letter

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Crinone

Progesterone

Summary for Crinone

Indications for Crinone

Pros and Cons for Crinone

Pros

Cons

Common Side Effects for Crinone

Warnings for Crinone

Summary for Prometrium

Indications for Prometrium

Pros and Cons for Prometrium

Pros

Cons

Common Side Effects for Prometrium

Warnings for Prometrium