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Beyfortus vs. Arexvy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Beyfortus

(nirsevimab)

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Arexvy

(RSV vaccine)

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Summary for Beyfortus

Prescription only

Beyfortus (nirsevimab or nirsevimab-alip) is an injection given to babies and children up to 24 months old. It's used to prevent them from getting very sick from respiratory syncytial virus (RSV). It's not an RSV vaccine. Instead, it's a monoclonal antibody that gives protection against the virus for a short time. Beyfortus (nirsevimab) is now part of the CDC Child Immunization Schedule. The usual dosage is 1 to 2 injections into the muscle during or at the start of the RSV season. It's well-tolerated with only a few side effects.

Indications for Beyfortus

  • Prevention of respiratory syncytial virus (RSV) in young children of certain ages
    • Newborns and infants born during or entering their first RSV season
    • Children up to 24 months old at risk of severe RSV illness through their second RSV season

Pros and Cons for Beyfortus

Pros

  • Given during one medical visit
  • Can lower the risk of severe RSV-related illness by about 70% in full-term and premature babies
  • Not many side effects

Cons

  • Injection can be uncomfortable
  • Protection might only last for about 5 months
  • Not known if it's safe or if it works well for children older than 24 months

Common Side Effects for Beyfortus

  • Side effects aren't common. See Other Side Effects.

Warnings for Beyfortus

  • Severe allergic reaction
  • Caution use in children with bleeding problems

Summary for Arexvy

Prescription only

Arexvy (RSV vaccine) is the first FDA-approved vaccine to help lower your risk of getting serious lung infections caused by respiratory syncytial virus (RSV). You can get it if you're age 60 or older, and in some cases starting at age 18 if you have a higher risk of severe illness from RSV. Arexvy (RSV vaccine) is given once as a single injection into the muscle. Common side effects include tiredness, muscle pain, and injection site reactions like pain, swelling, or redness.

Indications for Arexvy

Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:

  • Adults 60 years and older
  • Adults 18 to 59 years old who have a higher risk of illness due to RSV

Pros and Cons for Arexvy

Pros

  • Reduces the risk of RSV-related lung infections
  • Only need one dose
  • Can be given with other vaccines

Cons

  • Injection might be uncomfortable
  • Common side effects include tiredness and muscle pain
  • Not approved for use in pregnancy

Common Side Effects for Arexvy

18 to 49 years old:

  • Pain at the injection site (76%)
  • Muscle pain (60%)
  • Tiredness (60%)
  • Headache (44%)
  • Joint pain (28%)

50 to 59 years old:

  • Pain at the injection site (76%)
  • Tiredness (40%)
  • Muscle pain (36%)
  • Headache (32%)
  • Joint pain (23%)

60 years and older:

  • Pain at the injection site (61%)
  • Tiredness (34%)
  • Muscle pain (29%)
  • Headache (27%)
  • Joint pain (18%)

Warnings for Arexvy

  • Guillain-Barré syndrome
  • Severe allergic reaction
  • Fainting
  • Weaker vaccine protection

Prices with our coupons for Beyfortus vs. Arexvy

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Beyfortus1 carton / five 0.5ml prefilled syringes of 50mg/0.5ml
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Arexvy1 carton / 1 dose
$312.07-
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