Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Azelastine nasal spray, available as both Astepro Allergy (over-the-counter) and a prescription version, is an antihistamine used to treat nasal symptoms due to allergies, such as a runny or stuffy nose. Both versions work by blocking histamine to relieve these symptoms. However, there are some differences between the two. Astepro Allergy is available over-the-counter in a 0.15% strength and is suitable for adults and children 6 years and older. The prescription version comes in both 0.1% and 0.15% strengths and can also treat non-allergic nasal symptoms. The prescription version is available as a lower-cost generic, while Astepro Allergy is branded. Both forms can cause side effects like a bitter taste and nasal discomfort, but the prescription version has a higher incidence of side effects like headaches and sleepiness. Additionally, the prescription version may require more frequent dosing, typically twice a day, compared to the once or twice daily dosing of Astepro Allergy.
Astepro allergy (azelastine)
Azelastine nasal spray
Astepro allergy (azelastine)
Azelastine nasal spray
Summary of Astepro vs. Astelin
Summary for Antihistamine
Astepro Allergy (azelastine) is an antihistamine nasal spray that's used to treat nasal symptoms due to allergies, such as stuffy nose, sneezing, and runny nose. Astepro Allergy (azelastine) is available over-the-counter (OTC) for adults and children 6 years and older. The strength of Astepro Allergy (azelastine) is 0.15%. The dosage depends on your age, but it's usually sprayed into the nose once or twice a day. Side effects can include a bitter taste in the mouth, nasal discomfort, and sneezing.
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Note: Azelastine nasal spray is also available by prescription in 0.1% and 0.15% strengths.
Summary for Antihistamine
Prescription only
Azelastine nasal spray is an antihistamine that treats allergies and nasal symptoms, such as runny or stuffy nose. The 0.1% and 0.15% strengths of the azelastine nasal spray are available with a prescription for adults and children. It's sprayed into the nostrils typically twice a day. Prescription azelastine nasal spray is a lower-cost generic. Possible side effects include a bitter taste in the mouth and nasal discomfort.
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Note: Azelastine 0.15% nasal spray is also available over the counter under the brand name Astepro Allergy.
Indications of Astepro vs. Astelin
Indications for
Short-term relief of nasal symptoms due to allergies:
•Stuffy nose
•Runny nose
•Sneezing
•Itchy nose
Indications for
•Seasonal allergy symptoms related to the nose
•Year-round allergy symptoms related to the nose - azelastine 0.15% spray only