ACAM2000 vs. Jynneos for Smallpox and Mpox: Important Differences and Potential Risks.

ACAM2000

Jynneos

Summary for ACAM2000

Prescription only

ACAM2000 is a live vaccine that's used to prevent smallpox and mpox. It's FDA approved for certain people who are at high risk of being exposed to these viruses. The vaccine is administered as a single dose using a special method where a healthcare professional makes a few small pricks on your skin. A small blister will form at the spot where it was given, showing that the vaccine is working. Common side effects can include redness or pain at the injection site, headache, and tiredness.

Indications for ACAM2000

Prevention of smallpox and mpox

Pros and Cons for ACAM2000

Pros

Protects against both smallpox and mpox
Not a routine vaccine that everyone needs to get
Only one dose is needed to complete vaccination

Cons

Given as multiple pricks into the skin
Risk of serious side effects, including heart and skin problems
Requires careful aftercare to prevent the virus from spreading

Common Side Effects for ACAM2000

Itching at the injection site (up to 92%)
Redness at the injection site (up to 74%)
Pain at the injection site (up to 67%)
Lymph node pain (up to 57%)
Headache (up to 50%)
Tiredness (up to 48%)
Swelling at the injection site (up to 48%)
Muscle pain (up to 46%)
Feeling unwell (up to 37%)
Feeling hot (up to 32%)

Warnings for ACAM2000

Serious health problems
Heart problems
Eye infections
Severe skin reactions
Harm to unborn baby
Severe allergic reactions
Prevent spreading the vaccine virus
Delay blood and organ donation

Summary for Jynneos

Prescription only

Jynneos is a vaccine that helps lower your risk of getting smallpox and monkeypox infections. This vaccine is only approved by the FDA for adults 18 years and older who are at high risk for these infections. If you're looking to find this vaccine, use our monkeypox vaccine finder.

Indications for Jynneos

Prevention of smallpox and monkeypox in adults

Pros and Cons for Jynneos

Pros

Protects against multiple orthopoxviruses, including smallpox and monkeypox
People who've received smallpox vaccine in the past might only need one dose.
Can typically be given with other vaccines

Cons

Not studied in children
Only available as an injection, which can be painful
Must be given by a healthcare provider at an office, clinic, or pharmacy

Common Side Effects for Jynneos

Pain at injection site (up to 85%)
Redness at injection site (up to 81%)
Hard lump at injection site (up to 70%)
Swelling at injection site (up to 67%)
Itching at injection site (up to 43%)
Muscle pain (up to 43%)
Headache (up to 35%)
Feeling tired (up to 34%)

Warnings for Jynneos

Severe allergic reaction
Might not prevent monkeypox or smallpox

Prices with our coupons for ACAM2000 vs. Jynneos

Acam20001 vial / 0.3ml

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Jynneos1 vial / 0.5ml

$294.42$366.34

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ACAM2000 vs. Jynneos

ACAM2000

Jynneos

Summary for ACAM2000

Indications for ACAM2000

Pros and Cons for ACAM2000

Pros

Cons

Common Side Effects for ACAM2000

Warnings for ACAM2000

Summary for Jynneos

Indications for Jynneos

Pros and Cons for Jynneos

Pros

Cons

Common Side Effects for Jynneos

Warnings for Jynneos

Prices with our coupons for ACAM2000 vs. Jynneos

Browse medications by letter

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ACAM2000

Jynneos

Summary for ACAM2000

Indications for ACAM2000

Pros and Cons for ACAM2000

Pros

Cons

Common Side Effects for ACAM2000

Warnings for ACAM2000

Summary for Jynneos

Indications for Jynneos

Pros and Cons for Jynneos

Pros

Cons

Common Side Effects for Jynneos

Warnings for Jynneos