Muscle-relaxant-NSAID (nonsteroidal anti-inflammatory drug) combinations are used to treat muscle spasms, pain from musculoskeletal conditions, and inflammation. They also have other uses, such as managing tension headaches and post-surgical pain. These medications work by combining a muscle relaxant, which helps to ease muscle tension and spasms, with an NSAID, which reduces inflammation and pain. These combinations are typically available in oral forms, such as tablets or capsules. Examples include carisoprodol/aspirin (Soma Compound) and orphenadrine/aspirin (Norgesic). You can take these medications to help relieve pain and improve your ability to move comfortably.