Monobactam antibiotics are used to treat urinary tract infections, lower respiratory tract infections, and bloodstream infections. They also have other uses, such as managing symptoms of cystic fibrosis. Monobactams work by blocking the bacteria from making their protective cell walls, which helps to kill the bacteria causing the infection. Examples include aztreonam (Azactam), which is given as an injection. The inhalation form of aztreonam, Cayston, is used specifically for cystic fibrosis. These antibiotics can help treat your condition effectively.