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Aztreonam

AZTREONAM is a monobactam antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections. Compare monobactam antibiotics.
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What is Azactam?

Commonly Used Brand Name(s)Azactam

Therapeutic ClassificationsAntibiotic

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OverviewTOP

Aztreonam is an antibiotic that is used to treat infections caused by bacteria. It works by killing bacteria or preventing their growth.

Aztreonam is used to treat bacterial infections in many different parts of the body. It is sometimes given with other antibiotics. This medicine will not work for colds, flu, or other viral infections.

This medicine is available only with your doctor's prescription.

Proper UseTOP

To help clear up your infection completely, aztreonam must be given for the full time of treatment, even if you begin to feel better after a few days. Also, this medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, aztreonam must be given on a regular schedule.

DosingTOP

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • Adults and children 16 years of age and older: 1 to 2 grams injected slowly into a vein over a twenty- to sixty-minute period. This is repeated every six to twelve hours.
    • Children up to 16 years of age: Dosage is based on body weight and must be determined by your doctor.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

AllergiesTOP

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

PediatricTOP

Studies have been done in children and have shown that aztreonam is effective in treating certain bacterial infections and that side effects in children are similar to those experienced by adults. Elevations of liver enzymes and reductions in white blood cell counts were seen in children who were given high doses of this medicine or who had more serious infections.

GeriatricTOP

Aztreonam has been tested in a limited number of patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults.

PregnancyTOP

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast FeedingTOP

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Liver disease—Patients receiving high doses of aztreonam for a long time, who also have severe liver disease, may have an increased chance of side effects

Chemical ClassificationsTOP

Monobactam
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