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Gonadotropin Releasing Hormone Antagonist / Estrogen / Progestin Combinations

The combination of a gonadotropin releasing hormone antagonist, estrogen, and progestin is used to treat heavy menstrual bleeding. These drugs work by preventing premature ovulation, increasing estrogen levels, and altering hormone levels.

Why are gonadotropin releasing hormone antagonist estrogen progestin combinations prescribed?

  1. Endometriosis (50%)
  2. Heavy Menstrual Bleeding (50%)

Key takeaways

Gonadotropin-releasing hormone antagonist / estrogen / progestin combinations are used to treat endometriosis and heavy menstrual bleeding caused by uterine fibroids. These medications work by lowering estrogen and progesterone levels in your body, while adding a small amount of these hormones back to lessen the chance of serious side effects. An example is relugolix / estradiol / norethindrone (Myfembree).

Prices for popular Gonadotropin Releasing Hormone Antagonist / Estrogen / Progestin Combinations medications
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Myfembree

as low as$1,203
RELUGOLIX; ESTRADIOL; NORETHINDRONE helps reduce heavy periods caused by uterine fibroids. It may also be used to treat pain from endometriosis. Relugolix works by decreasing the amount of estrogen and other hormones your body makes, which reduces heavy bleeding and pain. Estradiol lowers the risk of bone loss caused by relugolix. Norethindrone helps lower the risk of cancer that can be caused by estradiol. This medication contains the hormones estrogen and progestin.
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Oriahnn

as low as$1,167
ELAGOLIX; ESTRADIOL; NORETHINDRONE helps reduce heavy periods caused by uterine fibroids. Elagolix works by decreasing the amount of estrogen and other hormones your body makes, which reduces heavy bleeding and pain. Estradiol lowers the risk of bone loss caused by elagolix. Norethindrone helps lower the risk of cancer that can be caused by estradiol. This medication contains the hormones estrogen and progestin.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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