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C3 Inhibitors

C3 inhibitors are used to treat paroxysmal nocturnal hemoglobinuria. They work by preventing destruction of red blood cells and immune cell activation.

Why are c3 inhibitors prescribed?

  1. Macular Degeneration (33%)
  2. Autoinflammatory Syndromes (33%)
  3. Paroxysmal Nocturnal Hemoglobinuria (33%)

Key takeaways

C3 inhibitors are used to treat paroxysmal nocturnal hemoglobinuria (PNH) and geographic atrophy (GA) secondary to age-related macular degeneration. These medications work by inhibiting complement C3 proteins, which play a role in inflammation. C3 inhibitors are available as under-the-skin and into-the-eye injections. One example is pegcetacoplan (Empaveli, Syfovre).

Prices for popular C3 Inhibitors medications
Viewing 3 of 3 medications
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Empaveli

as low as$4,887
PEGCETACOPLAN treats paroxysmal nocturnal hemoglobinuria (PNH), a condition that causes low levels of red blood cells (anemia) and blood clots. It works by slowing down an overactive immune system, which reduces the breakdown of red blood cells.
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Syfovre

as low as$22,448
PEGCETACOPLAN treats macular degeneration, a condition that can cause vision loss. It works by helping to slow changes in vision.
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Veopoz

as low as$33,113
POZELIMAB treats CHAPLE disease. It works by slowing down an overactive immune system. This decreases symptoms. It is a monoclonal antibody.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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