carglumic acid
Carbaglu (carglumic acid) lowers blood ammonia levels within 24 hours and helps keep it low, but it must be taken before every meal.
What is Carbaglu (carglumic acid)?
What is Carbaglu (carglumic acid) used for?
- High blood ammonia
How Carbaglu (carglumic acid) works
Carbaglu (carglumic acid) replaces a key chemical in people who don't have a specific liver enzyme, N-acetylglutamate synthase (NAGS). NAGS normally helps your body get rid of extra ammonia (a waste chemical produced by your body).
Drug facts
| Common Brands | Carbaglu |
|---|---|
| Drug Class | Metabolic alkalosis agent |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription only |
Side effects of Carbaglu (carglumic acid)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Vomiting (26%)
- Stomach pain (17%)
- Fever (17%)
- Swelling of tonsils (17%)
- Diarrhea (13%)
- Headache (13%)
- Ear infection (13%)
Less Common Side Effects
- Common cold
- Fewer healthy red blood cells (anemia)
- Lower hemoglobin levels
- Infections
The following Carbaglu (carglumic acid) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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Pros and cons of Carbaglu (carglumic acid)
Pros
- Lowers ammonia levels within 24 hours
- Can be given as early as the first day of life
Cons
- Must be mixed with water and taken right before a meal
- Tastes sour or acidic
Pharmacist tips for Carbaglu (carglumic acid)
- Right before before you take Carbaglu (carglumic acid), put tablets in about half a teaspoon (2.5 milliliters) of water per tablet. Carefully stir and immediately swallow the mixture. If pieces of the tablet are still in the cup, repeat this step by adding water as needed until no more pieces remain.
- Take Carbaglu (carglumic acid) in 2 to 4 divided doses throughout the day. Don't swallow tablets whole or crush them. Don't mix Carbaglu (carglumic acid) in liquids other than water.
- Take Carbaglu (carglumic acid) immediately before meals.
- Carbaglu (carglumic acid) may be started as early as the first day of life, depending on how severe (bad) the infant's condition is.
- Store unopened containers in a refrigerator. After opening, store at room temperature in a tight container. Throw away 1 month after opening.
- Don't breastfeed while taking Carbaglu (carglumic acid) unless your healthcare provider told you to do so.
Risks and warnings for Carbaglu (carglumic acid)
Carbaglu (carglumic acid) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
High blood ammonia levels
Carbaglu (carglumic acid) lowers ammonia in the blood. If ammonia levels in the blood get too high and you aren't treated, brain damage and death may occur. Talk to your healthcare provider about which symptoms of high ammonia levels you should look out for. Your healthcare provider may suggest you eat less protein to help keep ammonia levels lower.
Carbaglu (carglumic acid) dosage
Tablet| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 200mg | 120 tablets | $19,286.70 | $160.72 |
