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Carbidopa / Levodopa / Entacapone Coupon - Carbidopa / Levodopa / Entacapone 150mg tablet
Carbidopa / Levodopa / EntacaponeGeneric Stalevo
CARBIDOPA; LEVODOPA; ENTACAPONE is used to treat Parkinson's disease. Carbidopa and entacapone help levodopa to work better. The lowest GoodRx price for the most common version of carbidopa / levodopa / entacapone is around $152.00, 65% off the average retail price of $435.83. Compare DDCI / COMT inhibitor combinations.
Prescription Settings
120 tablets
Carbidopa / Levodopa / Entacapone Coupon - Carbidopa / Levodopa / Entacapone 150mg tablet
carbidopa / levodopa / entacapone(generic)
120 tablets

Carbidopa / Levodopa / Entacapone Side Effects

What should I watch for?

Visit your doctor or health care professional for regular checks on your progress. Do not take any additional medicines for Parkinson's disease without first consulting with your health care provider.

Entacapone may increase the side effects caused by Levodopa; Carbidopa such as nausea or restless movements. If you notice an increase in or the appearance of certain side effects that occurred only while you are taking Levodopa; Carbidopa, contact your physician. The dose of Levodopa-Carbidopa may need to be lowered. Do not decrease your medicine dose without asking your doctor or health care professional.

You may get dizzy or have difficulty controlling your movements. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness. Avoid alcoholic drinks.

If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

You may experience a 'wearing off' effect prior to the time for your next dose of this medicine. You may also experience an 'on-off' effect where the medicine apparently stops working for anything from a minute to several hours, then suddenly starts working again. Tell your doctor or health care professional if any of these symptoms happen to you. Your dosage may need adjustment.

A high protein diet can slow or prevent absorption of levodopa. Avoid high protein foods near the time of taking this medicine to help prevent this problem. You may want to eat higher protein foods later in the day or in small amounts. Discuss your diet with your doctor or nutritionist.

Do not take iron supplements within 2 hours of taking this medicine. The iron may decrease the amount of levodopa in your system and decrease the effectiveness of the drug

If you have diabetes, you may get a false-positive result for sugar in your urine. Check with your doctor or health care professional.

This medicine may discolor your urine, saliva or sweat, making it look darker or red in color. This is of no cause for concern. However, this may stain clothing or fabrics.

There have been reports of increased sexual urges or other strong urges such as gambling while taking some medicines for Parkinson's disease. If you experience any of these urges while taking this medicine, you should report it to your health care provider as soon as possible.

You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.

This medicine may cause a decrease in vitamin B6. You should make sure that you get enough vitamin B6 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common-Entacapone

Twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

Incidence not known-Carbidopa and Levodopa and/or Levodopa alone

Bleeding gums

bloody or black, tarry stools

bloody or cloudy urine

change in size, shape, or color of an existing mole

changes in skin color

chest pain, discomfort, or tightness


constricted pupil



difficult or labored breathing

difficulty with speaking


drooping eyelid (ptosis)

facial dryness

fast, irregular, or pounding heartbeat

fever with or without chills

general feeling of illness

hallucinations (seeing, hearing, or feeling things that are not there)


large, flat, blue, or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

loss of bladder control

lower abdominal or stomach pain

lower back or side pain

mole that leaks fluid or bleeds

muscle cramps or spasms

muscle pain or stiffness

muscle trembling, jerking, or stiffness



painful or difficult urination

pinpoint red spots on the skin

raised red swellings on the skin, the buttocks, legs, or ankles


severe mental changes

shakiness and unsteady walk

shuffling walk

sore throat

sores, ulcers, or white spots on the lips or in the mouth


swollen glands

trembling, or other problems with muscle control or coordination

unusual bleeding or bruising

unusual tiredness or weakness


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common-Entacapone

Absence of or decrease in body movement



urine discoloration

Less common-Entacapone

Acid or sour stomach



bitter, sour, or unusual taste in the mouth


burning feeling in the chest or stomach

dry mouth

excess air or gas in the stomach or intestines


full feeling



increased sweating



lack or loss of strength

passing gas


sleepiness or unusual drowsiness

stomach discomfort or upset

swollen mouth and tongue

tenderness in the stomach area

trouble sleeping

urge to have bowel movement

Incidence not known-Carbidopa and Levodopa and/or Levodopa alone

Being forgetful

bladder pain

blurred vision

body aches or pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning and upper abdominal or stomach pain

burning sensation of the tongue

clenching, gnashing, or grinding teeth

confusion about identity, place, and time

dark saliva

dark sweat

decreased mental acuity

difficulty swallowing


double vision

ear congestion

enlarged pupils

excessive watering of the mouth


false or unusual sense of well-being

feeling like you will pass out

feeling of warmth

feeling sad or empty


hair loss



hives or welts

increased blinking

increased interest in sexual ability, desire, drive, or performance

increased interest in sexual intercourse

lack of appetite

large, hard skin blisters

leg pain

loss of voice

muscle spasm, especially of the neck and back

nasal congestion



pain in the chest below the breastbone

painful or prolonged erection of the penis

pharyngeal pain

pounding in the ears

problems with memory or speech

redness of the face, neck, arms, and occasionally upper chest

runny nose

sense of stimulation

skin rash


slow movement

slow or fast heartbeat

slow reflexes



tremor, increased

trouble concentrating

trouble recognizing objects

trouble thinking and planning

urinary frequency

urinary retention

weight gain

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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