The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Involuntary movements (dyskinesia, 25%)
- Nausea (14%)
- Rapid involuntary movements (10%)
- Diarrhea (10%)
- Changes in the color of your urine (10%)
- Slow involuntary movements (9%)
- Stomach pain (8%)
- Dizziness (8%)
- Constipation (6%)
- Tiredness (6%)
- Back pain (5%)
Less Common Side Effects
- Vomiting
- Indigestion
- Dry mouth
- Shortness of breath
- More sweating
- Anxiety
- Weakness
Stalevo serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Withdrawal symptoms after treatment changes (e.g., stopping suddenly): very high fevers, sweating, confusion, irregular pulse, muscle stiffness, changes in breathing, changes in blood pressure
- Severe muscle damage (rhabdomyolysis): muscle aches, soreness, cramping, dark-colored urine
- Depression
- Suicidal thoughts or behavior
Source: DailyMed
The following Stalevo side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common-Entacapone
Twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
Incidence not known-Carbidopa and Levodopa and/or Levodopa alone
Bleeding gums
bloody or black, tarry stools
bloody or cloudy urine
change in size, shape, or color of an existing mole
changes in skin color
chest pain, discomfort, or tightness
constricted pupil
convulsions
difficult or labored breathing
difficulty with speaking
drooping eyelid (ptosis)
facial dryness
fast, irregular, or pounding heartbeat
fever with or without chills
general feeling of illness
hallucinations (seeing, hearing, or feeling things that are not there)
hoarseness
large, flat, blue, or purplish patches in the skin
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of appetite
loss of bladder control
lower abdominal or stomach pain
lower back or side pain
mole that leaks fluid or bleeds
muscle cramps or spasms
muscle pain or stiffness
muscle trembling, jerking, or stiffness
painful or difficult urination
pinpoint red spots on the skin
raised red swellings on the skin, the buttocks, legs, or ankles
restlessness
severe mental changes
shakiness and unsteady walk
shuffling walk
sores, ulcers, or white spots on the lips or in the mouth
sweating
swollen glands
trembling, or other problems with muscle control or coordination
unusual bleeding or bruising
unusual tiredness or weakness
vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common-Entacapone
Acid or sour stomach
belching
bitter, sour, or unusual taste in the mouth
bloated
burning feeling in the chest or stomach
excess air or gas in the stomach or intestines
fear
full feeling
hyperventilation
increased sweating
indigestion
irritability
lack or loss of strength
passing gas
restlessness
sleepiness or unusual drowsiness
stomach discomfort or upset
swollen mouth and tongue
tenderness in the stomach area
trouble sleeping
urge to have bowel movement
Incidence not known-Carbidopa and Levodopa and/or Levodopa alone
Being forgetful
bladder pain
blurred vision
body aches or pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
burning and upper abdominal or stomach pain
burning sensation of the tongue
clenching, gnashing, or grinding teeth
confusion about identity, place, and time
dark saliva
dark sweat
decreased mental acuity
difficulty swallowing
discouragement
double vision
ear congestion
enlarged pupils
excessive watering of the mouth
fainting
false or unusual sense of well-being
feeling like you will pass out
feeling of warmth
feeling sad or empty
flushing
headache
hiccups
hives or welts
increased blinking
increased interest in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
lack of appetite
large, hard skin blisters
leg pain
loss of voice
muscle spasm, especially of the neck and back
nightmares
numbness
pain in the chest below the breastbone
painful or prolonged erection of the penis
pharyngeal pain
pounding in the ears
problems with memory or speech
redness of the face, neck, arms, and occasionally upper chest
sense of stimulation
skin rash
slow movement
slow or fast heartbeat
slow reflexes
swelling
tremor, increased
trouble concentrating
trouble recognizing objects
trouble thinking and planning
urinary frequency
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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