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Capozide

captopril / HCTZ
Used for Hypertension
Used for Hypertension

Captopril/hydrochlorothiazide is a combination of two medications used to treat high blood pressure. It was often used when blood pressure couldn't be controlled by captopril or hydrochlorothiazide alone, but this combination is no longer available.

Reviewed by:
reviewer
Yen Nguyen, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on October 27, 2021
BasicsFAQsInteractionsLatest newsPricesMedicare
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What is Captopril/hydrochlorothiazide?

How Captopril/hydrochlorothiazide works

Drug Facts

Common BrandsCapozide (brand no longer available)
Drug ClassACE inhibitor / Diuretic (water pill)
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Captopril/hydrochlorothiazide

What is captopril/hydrochlorothiazide?
Captopril/hydrochlorothiazide is a combination medication. Captopril works by causing the blood vessels to dilate (widen), which will allow the blood to flow more easily. Hydrochlorothiazide is a diuretic (water pill) that works by preventing your body from reabsorbing salt and water through your urine. Together, these medications work to lower your blood pressure.
Is captopril/hydrochlorothiazide still available?
No, there are currently no brand or generic versions available in the United States.
Why was captopril/hydrochlorothiazide discontinued?
It's not clear why captopril/hydrochlorothiazide was discontinued by different manufacturers. One manufacturer (Mylan) announced that there was a shortage of captopril/hydrochlorothiazide. It's likely that there is low demand for this medication, so the manufacturers stopped making it. The individual medications that make up this combination, captopril and hydrochlorothiazide, are still available as separate medications.
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interactions

Interactions between Captopril/hydrochlorothiazide and other drugs

Captopril/hydrochlorothiazide may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Captopril/hydrochlorothiazide. Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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