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Cabenuva

Cabenuva Dosage

Kristianne Hannemann, PharmDDaisy Chau, PharmD
Reviewed by Kristianne Hannemann, PharmD, Daisy Chau, PharmD
Last reviewed on June 6, 2025

Typical dosage for Cabenuva

Cabenuva is approved for adults and teens ages 12 and older, weighing at least 35 kg (77 lbs). The dose depends on how often you get the injections.

  • Once-a-month: The typical starting dose is two separate injections — 600 mg of cabotegravir and 900 mg of rilpivirine — into the buttock muscle for the first month. Afterwards, the maintenance dose is 2 separate injections — 400 mg of cabotegravir and 600 mg of rilpivirine — given once a month.
  • Every-other-month: The typical starting dose is two separate injections — 600 mg of cabotegravir and 900 mg of rilpivirine — into the buttocks muscle once a month for the first 2 months. Afterwards, the maintenance dose is the same — 600 mg of cabotegravir and 900 mg of rilpivirine — given once every other month starting at month 4.

*Note: Before starting Cabenuva, your prescriber might have you take Vocabria (cabotegravir) and Edurant (rilpivirine) tablets by mouth for about a month to make sure you can tolerate the injections.

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