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Betaseron

Betaseron Side Effects

Robert Chad Hakim, PharmD, BCCCPConnie Zheng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Connie Zheng, PharmD
Last reviewed on December 15, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low blood cell counts (86%)
  • Injection site reactions: pain, swelling, bleeding (78%)
  • Flu-like symptoms: fever, chills, muscle pain, weakness, sweating (57%)
  • Muscle weakness (53%)
  • Headache (50%)
  • Pain (42%)
  • Stiff muscles (40%)
  • Fever (31%)
  • Muscle pain (23%)
  • Chills (21%)
  • Difficulty sleeping (21%)
  • Rash (21%)
  • Loss of balance/coordination (17%)
  • Stomach pain (16%)
  • Swelling in legs or hands (12%)
  • Urinating more (11%)

Less Common Side Effects

  • Chest pain
  • Uterine bleeding
  • Sexual dysfunction
  • General weakness/fatigue
  • High blood pressure
  • Difficulty breathing

Betaseron serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion
  • Serious allergic reactions: hives, itching, swelling of face or tongue, difficulty breathing
  • Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, unable to exercise, tiredness, weakness
  • Injection site necrosis (skin cell death): blue-black discoloration, swelling, broken skin
  • Serious infections: fever, tiredness, chills, cough, trouble breathing
  • Blood problems: purple bruises or pin-point dots on the skin, pale skin, yellowing of the skin or whites of your eyes, fever, tiredness, confusion, difficulty breathing, not able to make urine
  • Depression or suicidal ideation
  • Seizures

Source: DailyMed

The following Betaseron side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

break in the skin at the injection site, with blue-black discoloration, swelling, or drainage of fluid

flu-like symptoms including chills, fever, generalized feeling of discomfort or illness, increased sweating, and muscle pain

headache or migraine

hives, itching, or swelling at the injection site

irregular or pounding heartbeat

redness, pain, or feeling of heat at the injection site

stuffy nose

Less common

Bloody or cloudy urine

breast pain

changes in vision

cold hands and feet

difficult, burning, or painful urination

fast or racing heartbeat

frequent urge to urinate

pain

pelvic pain

swollen glands

troubled breathing

unusual weight gain

Rare

Abnormal growth in the breast

benign lumps in the breast

bleeding problems

bloating or swelling

changes in menstrual periods

confusion

convulsions (seizures)

cyst (abnormal growth filled with fluid or semisolid material)

decreased sexual ability in males

dry, puffy skin

feeling cold

hyperactivity

increased muscle tone

increased urge to urinate

loss of memory

mental depression with thoughts of suicide

problems with speaking

red, itching, or swollen eyes

swelling of the front part of the neck

unusual weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

diarrhea

dizziness

loss of voice

menstrual pain or other changes

unusual tiredness or weakness

Less common

Anxiety

drowsiness

hair loss

vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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