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Auvi-Q Coupon - Auvi-Q 2 auto-injectors of 0.3mg package

Auvi-Q

epinephrine
Used for Anaphylaxis
Used for Anaphylaxis

Auvi-Q (epinephrine) is a life-saving injectable medication used to relieve severe allergic reactions (e.g., anaphylaxis). It's available as a pre-filled auto-injector device that talks you through the injection process. You inject it into the muscle or under the skin of the middle of the outer thigh, and it can be used in people of all ages who weigh at least 16.5 lbs. Auvi-Q (epinephrine) can raise your blood pressure and open up your airways to help you breathe easier. Side effects of this medication include nervousness, high blood pressure, headache, and fast heart rate.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Daisy Chau, PharmD
Last reviewed on October 5, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Auvi-Q (epinephrine)?

What is Auvi-Q (epinephrine) used for?

How Auvi-Q (epinephrine) works

Auvi-Q (epinephrine) is a non-selective alpha- and beta-adrenergic receptor agonist that acts on receptors (signaling proteins) throughout the body. In doing so, it keeps your blood pressure from dropping too low, raises your heart rate, and opens your lungs so you can breathe normally. It also helps with swelling, itching, rashes, hives, and stomach issues linked to an allergic reaction.

Are you looking for information on epinephrine injection (EpiPen) instead?

Drug Facts

Common BrandsAuvi-Q
Drug ClassAdrenergic receptor agonist
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$750.87(save 61.51%)
Manufacturer exclusive discount
$289.00
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What are the side effects of Auvi-Q (epinephrine)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Feeling anxious, nervous, or restless
  • Shaking or tremors
  • Weakness
  • Dizziness
  • Sweating
  • Racing heartbeat

Other Side Effects

  • Pale skin color
  • Nausea or vomiting
  • Headache
  • Difficulty breathing

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Irregular heart rhythm (arrhythmias): fatigue, weakness, dizziness, shortness of breath, chest pain, sweating
  • High blood pressure: headache, chest pain, dizziness, blurry vision
  • Serious infection at injection site: skin redness, tenderness, swelling, warmth

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Abnormal or decreased touch sensation

anxiety

arm, back, or jaw pain

bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

blurred vision

chest pain, tightness, heaviness, or discomfort

cold, pale, or bluish color of the skin of the fingers or toes

confusion

difficulty in speaking

dizziness

double vision

fainting

fast, slow, irregular, pounding, or racing heartbeat or pulse

headache

inability to move the arms, legs, or facial muscles

inability to speak

nausea

numbness, tingling, or pain in the fingers

paleness of the skin

pounding in the ears

restlessness

shakiness in the legs, arms, hands, or feet

slow speech

sweating

trembling or shaking of the hands or feet

trouble breathing

unusual tiredness or weakness

vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Agitation

coldness of the skin

confusion

decreased awareness or responsiveness

decreased urine output

depression

drowsiness

hostility

irritability

lightheadedness

loss of consciousness

muscle twitching

rapid weight gain

rapid, deep breathing

seizures

severe sleepiness

stomach cramps

swelling of the face, ankles, or hands

unusual drowsiness, dullness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Auvi-Q (epinephrine)

thumbs-up

Pros

Includes voice instructions to guide you through giving an injection

Also contains visual instructions on the device

Can be used in young children who weigh at least 16.5 pounds

If needed, can be injected through clothing

thumbs-down

Cons

Must be stored at room temperature, so it shouldn't be kept in a hot or cold car

Can cause heart-related side effects (e.g., chest pain, irregular heartbeat)

Must know how to inject before you need it

Need to use the right dose for you or your child's body weight

pharmacist-tips

Pharmacist tips for Auvi-Q (epinephrine)

pharmacist

  • Always carry Auvi-Q (epinephrine) with you at all times so you can be prepared in case you have an allergic reaction. Make sure you're able to recognize the symptoms of anaphylaxis. If you need to give Auvi-Q (epinephrine), do so first and then call 911 right after.

    • Each Auvi-Q (epinephrine) carton comes with a trainer device that doesn't contain any medication or needle, so that you can practice at home before an emergency happens.

      • The Auvi-Q (epinephrine) auto-injector will work even if the voice instructions don't turn on.

        • Inject Auvi-Q (epinephrine) only into the middle of the outer thigh. Never inject into other parts of the body because the medication might not work as well. If necessary, you can inject through clothing.

          • If you're giving Auvi-Q (epinephrine) to a young child or infant, make sure to hold their leg still while giving the injection to avoid injury.

            • The Auvi-Q (epinephrine) auto-injector device delivers a single dose. Once it's been activated and used, don't try to reuse the same device or syringe again. If you need to repeat a second dose, make sure to use a brand new auto-injector.

              • Store Auvi-Q (epinephrine) at room temperature in the original container to protect it from light. Don't expose the medication to extreme heat (e.g., car glove box) or cold (e.g., refrigerator or freezer) because this can damage the medication and make it not work well for you.

                • Ask your provider how to safely dispose of Auvi-Q (epinephrine). It has batteries that contain perchlorate, so some states require it to be put in a special hazardous waste.

                  faqs

                  Frequently asked questions about Auvi-Q (epinephrine)

                  Is Auvi-Q (epinephrine) the same as EpiPen?
                  Both Auvi-Q (epinephrine) and EpiPen contain epinephrine. The main difference is that Auvi-Q (epinephrine) has automated voice guidance that gives you instructions on how to use the auto-injector when it's turned on. EpiPen doesn't have voice guidance.
                  How do you administer Auvi-Q (epinephrine)?
                  At the first sign of a severe allergic reaction, inject Auvi-Q (epinephrine) into the muscle, or under the skin, into the side of your thigh. If needed, you can give Auvi-Q (epinephrine) through clothing. Never inject Auvi-Q (epinephrine) into the veins or into any other part of your body. Each prefilled auto-injector contains one dose. Make sure to review the instructions and ask your provider or pharmacist if you have any questions.
                  How long does Auvi-Q (epinephrine) last?
                  Auvi-Q (epinephrine) works very quickly to relieve symptoms of a serious allergic reaction. But its effects don't last very long. Get medical help right away after you use the medication. This is because Auvi-Q (epinephrine) wears off quickly and there's a risk that you can have another reaction in minutes or hours. If needed, you can give yourself another dose of Auvi-Q (epinephrine) while waiting for medical help to arrive. But if you need more than two doses of Auvi-Q (epinephrine), it should be done under the supervision of a healthcare provider.
                  Does Auvi-Q (epinephrine) raise heart rate or blood pressure?
                  Yes, Auvi-Q (epinephrine) raises your blood pressure and heart rate. This is important during a severe allergic reaction, which can be life-threatening because it can cause a drop in blood pressure and heart rate. So Auvi-Q (epinephrine) is helpful in someone who's having an allergic reaction because it raises blood pressure and heart rate so that blood continues to flow properly through your body.
                  Can you use Auvi-Q (epinephrine) if it's expired?
                  After the expiration date, Auvi-Q (epinephrine) might not work as well to treat a serious allergic reaction. This could have life-threatening consequences. To be safe, once Auvi-Q (epinephrine) expires, throw it away and contact your provider for a new one.
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                  What are the risks and warnings for Auvi-Q (epinephrine)?

                  Auvi-Q (epinephrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Emergency medical care

                  Get medical help right away after you use Auvi-Q (epinephrine), even if you start feeling better. It's best to have a healthcare provider monitor your condition just in case the symptoms come back or if you require additional treatments. Auvi-Q (epinephrine) can't replace immediate medical attention.

                  risk-warning

                  Injection-related problems

                  Auvi-Q (epinephrine) is only meant to be injected into the muscle or under the skin of the outer thigh. Don't inject it by any other route or into any other area of the body. Doing so can lead to serious medical problems.

                  If you're giving Auvi-Q (epinephrine) to a child, try your best to hold the child's leg firmly in place and to prevent them from moving too much or kicking to prevent needle injuries.

                  risk-warning

                  Risk of skin infection

                  Serious skin infections are rare, but can happen after using Auvi-Q (epinephrine). To lower this risk, don't inject this medication into the buttock area. If you notice the Auvi-Q (epinephrine) injection site becomes red, warm, swollen, or tender, seek medical care so you can be tested for an infection and receive treatment, if needed.

                  risk-warning

                  Okay to use in people with sulfite allergy

                  Auvi-Q (epinephrine) might contain sulfites. But if you're experiencing a severe, life-threatening allergic reaction and have an allergy to sulfites, you should still use Auvi-Q (epinephrine) because it's a life-saving medication.

                  risk-warning

                  High blood pressure and heart rate

                  • Risk factors: Receiving Auvi-Q (epinephrine) through the veins | History of heart problems | Taking medications that affect heart rate or blood pressure

                    Auvi-Q (epinephrine) raises blood pressure and heart rate. Let your provider know if you experience any trouble breathing, chest pain, dizziness, changes in vision, or headache. These could be signs that your blood pressure or heart rate is too high and you might need to receive treatment after your allergic reaction is gone.

                    dosage

                    Auvi-Q (epinephrine) dosage forms

                    The average cost for 1 package of 2 auto-injectors of 0.3mg of Auvi-Q (epinephrine) is $289.00 with a free GoodRx coupon. This is 61.51% off the average retail price of $750.87.
                    package
                    Package
                    DosageQuantityPrice as low asPrice per unit
                    2 auto-injectors of 0.1mg1 package$289.00$289.00
                    2 auto-injectors of 0.15mg1 package$289.00$289.00
                    2 auto-injectors of 0.3mg1 package$289.00$289.00

                    Typical dosing for Auvi-Q (epinephrine)

                    Your provider will prescribe Auvi-Q (epinephrine) based on your body weight. Auvi-Q (epinephrine) is available in cartons that contain two prefilled auto-injectors and an Auvi-Q Trainer. Each auto-injector contains a single and complete dose.

                    You can inject the medication into the muscle or under the skin in the middle of the outer thigh (even through clothing) when you feel an allergic reaction. Call 911. While you're waiting for help to arrive, you can repeat the dose if symptoms don't go away.

                    • 66 lbs or more: The typical dose is 0.3 mg.

                    • 33 lbs to 66 lbs: The typical dose is 0.15 mg.

                    • 16.5 lbs to 33 lbs: The typical dose is 0.1 mg.

                    interactions

                    Interactions between Auvi-Q (epinephrine) and other drugs

                    Auvi-Q (epinephrine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Auvi-Q (epinephrine). Please note that only the generic name of each medication is listed below.

                    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    drug-cost

                    How much does Auvi-Q (epinephrine) cost?

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                    Auvi-Q (brand)
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                    alternatives

                    What are alternatives to Auvi-Q (epinephrine)?

                    There are a number of medications that your doctor can prescribe in place of Auvi-Q (epinephrine). Compare a few possible alternatives below.
                    Auvi-Q (epinephrine)
                    Used for:
                    $289.00 Lowest GoodRx priceView Prices
                    Epinephrine (Epipen)
                    Used for:
                    $171.26 Lowest GoodRx priceView Prices
                    latest news

                    What is the latest news about Auvi-Q (epinephrine)?

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                    Can You Use an EpiPen After It Expires?

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                    EpiPen is only available with a prescription, but you can get a refill without seeing a doctor in person. Telehealth services like GoodRx Care allow you to get your prescription refilled and delivered to your pharmacy — often on the same day. Your insurance plan may cover your refill but it’s best to check with your plan first.

                    Here’s How to Get an Epipen Refill Without Seeing a Doctor in Person

                    EpiPen is only available with a prescription, but you can get a refill without seeing a doctor in person. Telehealth services like GoodRx Care allow you to get your prescription refilled and delivered to your pharmacy — often on the same day. Your insurance plan may cover your refill but it’s best to check with your plan first.
                    Last month, we introduced GoodRx Care, offering online medical visits starting at $20. Today, we’re excited to announce that we’re expanding this service to include prescriptions for EpiPen and similar medication options for anaphylaxis.

                    GoodRx Care Now Refilling EpiPen Prescriptions for Anaphylaxis

                    Last month, we introduced GoodRx Care, offering online medical visits starting at $20. Today, we’re excited to announce that we’re expanding this service to include prescriptions for EpiPen and similar medication options for anaphylaxis.
                    Where two years ago, EpiPen had nearly 90% of the market for the medication, today, the Epipen brand auto-injector accounts for just around 10% of fills. Instead, the generic version of Epipen now holds more than 60% of the market, with a generic version of the Adrenaclick auto-injector accounting for another 30%.

                    2 Years After the EpiPen Price Hike, Here’s What’s Changed

                    Where two years ago, EpiPen had nearly 90% of the market for the medication, today, the Epipen brand auto-injector accounts for just around 10% of fills. Instead, the generic version of Epipen now holds more than 60% of the market, with a generic version of the Adrenaclick auto-injector accounting for another 30%.
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                    References

                    Best studies we found

                    Dalal, R., et al. (2023). Epinephrine. StatPearls.

                    kaleo, Inc. (2019). How to use Auvi-Q.

                    kaleo, Inc. (2022). Auvi-Q- epinephrine injection, solution [package insert]. DailyMed.

                    View All References (1)

                    Srinivasan, A., et al. (2009). Perchlorate: Health effects and technologies for its removal from water resources. International Journal of Environmental Research and Public Health.

                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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