Arformoterol (Brovana) is a medication that can help people with chronic obstructive pulmonary disease (COPD) breathe easier. You breathe in the medication twice per day using a nebulizer. Studies show that arformoterol (Brovana) can help your lungs work better and lower the risk of hospitalizations due to worsening COPD symptoms.
Chronic obstructive pulmonary disease (COPD)
Arformoterol (Brovana) is a long-acting beta agonist (LABA). It works by relaxing the muscles in your lungs to open up your airways, making it easier to breathe.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Less common
blistering, crusting, irritation, itching, or reddening of the skin
bloating or swelling of the face, arms, hands, lower legs, or feet
bloody or cloudy urine
blurred vision
chest discomfort or tightness
chills
cold sweats
confusion
cool, pale skin
decreased urination
difficult or labored breathing
difficult, burning, or painful urination
difficulty swallowing
dilated neck veins
dizziness
extreme tiredness or weakness
fainting
fast heartbeat
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
headache
increase in heart rate
increased hunger
increased thirst
increased urination
irregular breathing
irregular heartbeat, recurrent
lightheadedness
loss of appetite
loss of consciousness
mood changes
muscle aches and pains
nervousness
nightmares numbness or tingling in the hands, feet, or lips
pain or discomfort in the arms, jaw, back, or neck
pain or tenderness around the eyes and cheekbones
pounding, slow heartbeat
rapid breathing
rapid weight gain
seizures
shakiness
slurred speech
stomach pain
stuffy or runny nose
sunken eyes
sweating
unusual tiredness or weakness
unusual weight gain or loss
vomiting
wrinkled skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Arm, back, or jaw pain
blurred vision
chest discomfort, tightness, or heaviness
confusion
decreased urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
fast, pounding, or irregular heartbeat or pulse
increased thirst
loss of consciousness
mood changes
muscle pain, cramps, or tremors
nervousness
numbness or tingling in the hands, feet, or lips
pounding in the ears
rapid, deep breathing
restlessness
seizures
slow heartbeat
stomach cramps
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Blindness
bloody, black, or tarry stools
blurred vision
burning feeling in the chest or stomach
change in vision
change in voice
decreased vision
difficulty in moving
indigestion
leg cramps
muscle stiffness
pain, swelling, or redness in the joints
pelvic pain
skin color changes
stomach upset
tearing
tenderness in the stomach area
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
A recommended medication for COPD
Helps with lung function and lowers the number of COPD attacks that require hospitalization
Some people might find arformoterol (Brovana) easier to use than inhalers.
Takes about 5 to 10 minutes to take each dose
Might not work as well as other types of long-acting inhaled medications like Spiriva (tiotropium)
Need to use with nebulizer machine, which isn't ideal for someone who's on the go
Use arformoterol (Brovana) as prescribed twice every day at the same times each day. This helps make sure the medication can work best for you. Don't take any extra doses or use other similar long-acting medications because of the risk of severe and life-threatening side effects from taking too much.
Always have your rescue medication (nebulized albuterol (Accuneb) or albuterol inhaler (ProAir, Ventolin)) handy in case you have sudden trouble breathing. Arformoterol (Brovana) doesn't work to treat sudden difficulty breathing.
Carefully read the instructions on how to use arformoterol (Brovana) with a nebulizer machine. Ask your provider or pharmacist if you have any questions about using the medication.
Keep the vials of arformoterol (Brovana) solution in the original foil pouch and in the refrigerator. After opening the pouch, keep any unused vials in the foil pouch in the refrigerator.
You can also keep unopened foil pouches of arformoterol (Brovana) at room temperature for up to 6 weeks. Throw it away if you haven't used it within 6 weeks at room temperature or if it's past the expiration date, whichever is sooner.
Before using each vial of arformoterol (Brovana), check the solution to make sure it's colorless. If it's discolored, throw the vial away and use a new one to be sure it's safe for you to use.
Sit in a comfortable, upright position during your breathing treatment. Breathe as calmly, deeply, and evenly as possible until there's no more mist in the nebulizer.
Clean your nebulizer after each time you use it. This helps prevent lung infections that can happen if you use a nebulizer machine that isn't cleaned well.
Call your provider if your breathing gets worse. Also contact your provider if you're using your rescue medication more often than usual. These could be signs you need a change in your COPD medications.
Arformoterol (Brovana) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Although rare, arformoterol (Brovana) can sometimes cause a muscle spasm in your lungs (bronchospasm). This can lead to difficulty breathing, wheezing, cough, and chest discomfort. If you become short of breath after using arformoterol (Brovana), get medical help right away.
Risk factors: High blood pressure | Heart failure | Heart rate or rhythm problems | Using more arformoterol (Brovana) than recommended
Arformoterol (Brovana) can cause changes in your blood pressure and heart rate. If you have high blood pressure or other heart problems, arformoterol (Brovana) can make it worse, especially if you take the medication more often than instructed. Watch out for worsening signs and symptoms of your heart condition. Tell your provider if you develop dizziness, fatigue, tremor, rapid heartbeat, or weakness while taking arformoterol (Brovana).
Allergic reactions to arformoterol (Brovana) are possible, including life-threatening reactions like facial swelling, shock, and anaphylaxis (closing of the throat). Get medical attention right away if you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after using arformoterol (Brovana).
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
2ml of 15mcg/2ml | 60 vials | $85.82 | $1.43 |
The typical dose is 15 mcg (one vial) inhaled through the mouth by nebulization twice per day (once in the morning and once in the evening).
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using without an inhaled corticosteroid in people with asthma
Chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease (COPD)
Prevention of exercise-induced bronchospasm (EIB) in people ages 4 years and older
Maintenance treatment of asthma in people ages 4 years and older (as an add-on medication to an inhaled corticosteroid (ICS))
Maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults
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Donohue, J. F., et al. (2014). One-year safety and efficacy study of arformoterol tartrate in patients with moderate to severe COPD. Chest.
American Thoracic Society. (2020). Nebulizer breathing treatments at home. Patient Education | Information Series.
Global Initiative for Chronic Obstructive Lung Disease. (2020). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2023 report).
Slate Run Pharmaceuticals. (2023). Arformoterol tartrate inhalation [package insert]. DailyMed.
King, P. (2008). Role of arformoterol in the management of COPD. International Journal of Chronic Obstructive Pulmonary Disease.
Almadhoun, K., et al. (2022). Bronchodilators. StatPearls.
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