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Arcalyst

Arcalyst Side Effects

Ally Tsai, PharmDDaisy Chau, PharmD
Reviewed by Ally Tsai, PharmD, Daisy Chau, PharmD
Last reviewed on May 16, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain, itching, and swelling around the injection site (48%)
  • Upper respiratory tract infection (26%)

Note: Side effects listed above are for people with CAPS. Similar side effects were reported in people with DIRA and RP.

Less Common Side Effects

  • Cough
  • Feeling numb
  • Nausea
  • Diarrhea
  • Urinary tract infection (UTI)
  • Ear infection
  • Rash
  • Sore throat

Arcalyst serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious infections: fever, cough, chills, sore throat, runny or stuffy nose, body aches, open sores, feeling tired
  • Allergic reaction: rash, swollen face, trouble breathing

Source: DailyMed

The following Arcalyst side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Cough
  • Diarrhea
  • Nausea
  • Numbness, decrease in sense of touch or sensation
  • Pain, redness, or irritation at injection site
  • Sinus pain or pressure around the face or forehead
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