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What does the drug tacrolimus do?

What does the drug tacrolimus do?
Tacrolimus works by stopping the activity of an enzyme (protein) in the body called calcineurin. Calcineurin plays a key role in activating T cells — white blood cells that help regulate immune responses. When an organ is transplanted into a new body, the recipient's immune system may recognize it as foreign and attack it. By blocking calcineurin, tacrolimus can make the immune system less active, making organ rejection less likely.  View original source
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