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Tadalafil (Cialis) is a phosphodiesterase-5 (PDE-5) inhibitor. It works by blocking a protein in the body called PDE-5.
For ED, blocking PDE-5 causes the muscles in the penis to relax. This allows the penis to fill with blood when you're sexually aroused. It helps you have an erection and maintain an erection.
For BPH, it's not fully clear how the medication works to help treat symptoms. But researchers think it helps relax the muscles in the prostate (a small gland in the groin).
