How does Polytrim (polymyxin B / trimethoprim) work?

Polytrim (polymyxin B / trimethoprim) is a combination of two antibiotics that work together to kill bacteria:

Polymyxin B: is a polypeptide antibiotic that breaks the outer protective covering that bacteria need to grow and survive.
Trimethoprim is an antifolate. It works by stopping bacteria from being able to make a substance (folic acid) that's needed for them to grow and survive.

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Polytrim (polymyxin B / trimethoprim) is a combination of two antibiotics that work together to kill bacteria:

Polymyxin B: is a polypeptide antibiotic that breaks the outer protective covering that bacteria need to grow and survive.
Trimethoprim is an antifolate. It works by stopping bacteria from being able to make a substance (folic acid) that's needed for them to grow and survive.

Was this article helpful?