Does semaglutide cause nausea and vomiting?

Nausea is the most common semaglutide side effect. Up to 20% of people receiving Ozempic for Type 2 diabetes reported nausea during clinical trials. And nausea was even more common with Wegovy for weight loss. Vomiting tends to be less common than nausea. You’re more likely to experience nausea and vomiting with higher semaglutide doses. Here are tips for managing nausea from semaglutide:

• Eat smaller, more frequent meals.
• Eat slowly and stop eating when you start to feel full.
• Avoid or minimize high-fat foods.
• Remain upright after you eat.
• Stay hydrated since dehydration can worsen nausea.
• Opt for low-fat, bland foods that are easy on your stomach.
• Try a home remedy, such as ginger.

If these changes don’t seem to help, talk to your healthcare team about medication options. They may recommend an over-the-counter (OTC) or prescription nausea medication for relief. But if your nausea is accompanied by severe pain in your upper and middle abdomen, get medical attention right away. This could be a sign of pancreatitis, which has been reported with semaglutide.