Alclometasone dipropionate is a low potency (strength) topical steroid medication that comes in both cream and ointment. It's used to relieve inflammation and itching from various skin conditions, such as eczema or allergic reactions. The medication can be used in adults and children 1 year and older. Typically, it's applied to the affected area(s) of the skin 2 or 3 times a day. While most people experience few to no side effects, some might have skin irritation or burning at the application site.
Inflammatory and itchy skin conditions
Alclometasone is a topical corticosteroid. It blocks certain substances in the body that cause inflammation which can lead to redness, itching, and swelling. This helps reduce inflammation in certain skin conditions.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Low potency topical steroid, so it has lower risk of side effects
Available in both cream and ointment
Can be used in children 1 year and older
Only used short term
Might not work as well for serious skin conditions
Applied multiple times a day
When applying alclometasone, make sure to gently massage it into the skin until the medication disappears.
Apply alclometasone only on skin that's not broken. Avoid open wounds or damaged skin because this could cause you to absorb more medication, leading to a higher risk of side effects. Don't take this medication by mouth, and never use it in your eyes, nose, or ears.
Don't use alclometasone on the face, armpits, or groin unless directed by your healthcare team.
Wash your hands before and after using alclometasone to help prevent getting the medication in your eyes.
Don't cover the treated area with a bandage after applying alclometasone unless your prescriber instructed you to. This can cause more medication to get absorbed into your body than intended. It can also raise your risk of side effects, like burning and irritation.
Alclometasone isn't meant to be used long term, so ask your healthcare team how long your treatment should last. Let your healthcare team know if you haven't had any improvement in your skin condition after 2 weeks. You might need to receive a different treatment.
Don't apply other topical steroids to the skin while you're using alclometasone unless your prescriber specifically said it's safe for you. Applying more than one topical steroid can raise your risk for side effects.
Alclometasone can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Applying other topical steroids at the same time | Applying alclometasone for a long period of time | Applying too much alclometasone on your skin | Covering the medicated area | Young children
If too much topical steroid is absorbed through the skin, it can interrupt your body's ability to make stress hormones and affect many bodily functions. For example, it can raise your blood sugar levels or cause your skin to bruise more easily. This is rare with alclometasone because it's a low-potency corticosteroid. But your risk is higher if you apply alclometasone for a long time or apply it over larger areas of skin. To prevent changes in hormone levels, your healthcare team will prescribe the lowest possible dose of alclometasone for the shortest amount of time.
In addition, if you suddenly stop using alclometasone after having done so for a long time and over a large skin area, you might experience topical steroid withdrawal (TSW). Some symptoms include itchy, burning, or flaky skin. Don't suddenly stop using alclometasone without talking to them first.
Alclometasone can lower your body's ability to fight infections, including infections on your skin. It's especially important to treat skin infections with an appropriate antifungal or antibacterial if you're using alclometasone. If you notice redness, pain, swelling, or pus where you are applying this medication, stop using it and talk to your prescriber right away.
Risk factors: Using a higher dose of alclometasone over a longer period of time
Using alclometasone longer than directed by your prescriber can raise your risk of different skin reactions, including skin thinning, stretch marks, burning, itching, irritation, dry skin, or rash. To prevent severe skin reactions from happening, your healthcare team will prescribe the lowest possible dose of alclometasone to treat your symptoms for the shortest amount of time. Let them know right away if you notice any new or worsening skin problems.
The typical dose is to apply a thin layer to the affected area(s) 2 or 3 times a day.
Skin inflammation
Skin rashes
Eczema
Psoriasis
Insect bites
Poison ivy or oak
Skin allergies
Dry scalp
Genital or rectal irritation
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Glenmark Pharmaceuticals Inc., USA. (2021). Alclometasone dipropionate cream; Alclometasone dipropionate ointment [package insert]. DailyMed.
InformedHealth.org. (2021). Eczema: Learn more – Steroids and other topical medications. Institute for Quality and Efficiency in Health Care.
Pippin, M. M., et al. (2023). Tinea cruris. StatPearls.
Sidbury, R., et al. (2023). Guidelines of care for the management of atopic dermatitis in adults with topical therapies. Journal of the American Academy of Dermatology.
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