Acthar Gel Dosage

In general, your dose depends on what condition you’re using Acthar Gel (corticotropin) for and how severe it is.

• Infantile spasms (ages 2 years and under): Your child's pediatrician will calculate the dose based on body surface area (BSA), which takes into account your child's weight and height. The typical dose is 75 units/m² injected into your child's muscle twice daily for 2 weeks.
• Multiple sclerosis: Your prescriber will determine your dose based on your symptoms. The typical dose ranges from 80-120 units injected into the muscle or under your skin, once daily for 2-3 weeks.
• Other conditions: Your prescriber will determine your dose based on your symptoms. The typical dose ranges from 40-80 units injected into the muscle or under your skin every 1 to 3 days.

After your treatment is over, your prescriber might have you slowly lower your dose over the course of a few days before stopping completely to avoid withdrawal symptoms.