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Xdemvy Coupon - Xdemvy 10ml of 0.25% eye dropper

Xdemvy

lotilaner
Used for Eye Inflammation
Used for Eye Inflammation

Xdemvy (lotilaner) is a newer, twice-daily eye drop that's used to treat Demodex blepharitis. This is an eye condition caused by mites that live on the skin. It's important to continue using Xdemvy (lotilaner) drops for 6 weeks to see the best results. While most people don't experience side effects from Xdemvy (lotilaner), some have reported a burning or stinging sensation when they put the drops in the eyes.

Reviewed by:
reviewer
Allison Gourley, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on September 24, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageAlternativesImagesReferencesPricesMedicare
basics-icon

What is Xdemvy (lotilaner)?

What is Xdemvy (lotilaner) used for?

How Xdemvy (lotilaner) works

Xdemvy (lotilaner) helps paralyze and kill Demodex mites by acting on their nervous system. These mites are what cause Demodex blepharitis, an inflammatory eye condition that affects your skin and eyelashes.

Drug Facts

Common BrandsXdemvy
Drug ClassOphthalmic agent
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
basics-icon

What are the side effects of Xdemvy (lotilaner)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Burning sensation of the eyes (10%)
  • Stinging sensation of the eyes (10%)

Other Side Effects

  • Red bump on the eyelid (from blocked oil gland or eye infection)
  • Swelling of the cornea

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Burning or stinging of the eyes after use
pros-and-cons

Pros and cons of Xdemvy (lotilaner)

thumbs-up

Pros

The only FDA-approved treatment for Demodex blepharitis

Not many serious side effects

Can be stored at room temperature

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Cons

Need to use for the full six-week course

Need to apply twice daily

Only available at certain specialty pharmacies (as of September 2023)

pharmacist-tips

Pharmacist tips for Xdemvy (lotilaner)

pharmacist

  • Make sure you wash your hands carefully before handling the Xdemvy (lotilaner) bottle and administering your drops to prevent contamination (spreading germs) which could cause an eye infection.

    • If you develop another eye condition (e.g. pink eye or trauma to your eye) or need eye surgery, let your provider know right away because they might want you to pause your Xdemvy (lotilaner) treatment.

      • Xdemvy (lotilaner) contains a preservative which can discolor your soft contact lenses. Make sure to remove your lenses before administering your eye drops, and wait 15 minutes before putting them back in.

        • Wait 5 minutes before using any other kind of eye drops with Xdemvy (lotilaner); this will make sure your eye absorbs enough of each medication.

          • It's unknown whether Xdemvy (lotilaner) is safe to use if you're pregnant or breastfeeding. While it's unlikely that a large amount of medication will get in your body or breastmilk, it's best to have a discussion with your provider if you're pregnant or planning to become pregnant before using this eye drop.

            faqs

            Frequently asked questions about Xdemvy (lotilaner)

            Can I use Xdemvy (lotilaner) along with other eye drops?
            Yes, you can use Xdemvy (lotilaner) along with other eye drops. But if you should wait at least 5 minutes after using Xdemvy (lotilaner) before putting in a different eye medication. This gives each medication time to get absorbed into the eye.
            Does Xdemvy (lotilaner) contain preservatives?
            Yes, Xdemvy (lotilaner) comes in a multi-use bottle and contains potassium sorbate which helps keep the medication free from germs. To minimize the risk of contamination, it's best practice to wash your hands before applying Xdemvy (lotilaner) and avoid touching the bottle tip.
            Can I use Xdemvy (lotilaner) if I'm wearing contact lenses?
            The preservative in Xdemvy (lotilaner), potassium sorbate, might cause your soft contact lenses to change colors. To avoid this from happening, remove your lenses before applying Xdemvy (lotilaner) drops. You can put your lenses back in after 15 minutes.
            What if I miss my Xdemvy (lotilaner) dose?
            If you forget your Xdemvy (lotilaner) dose, skip the missed dose and give your next scheduled dose. Don't double up to make up for the missed dose. Set yourself an alarm or reminder so that you won't miss future doses; using this medication every 12 hours for the full 6 week course will help make sure you get the most benefit from it.
            Do I need to refrigerate Xdemvy (lotilaner)?
            Don't store Xdemvy (lotilaner) in the fridge. You can keep it at room temperature until the expiration date on the bottle.
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            What are the risks and warnings for Xdemvy (lotilaner)?

            Xdemvy (lotilaner) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Risk of contamination

            Remember to wash your hands before using Xdemvy (lotilaner). Don't touch the tip of the Xdemvy (lotilaner) bottle onto your eye or to any surface. These steps help prevent contamination of the medication, eye infections, and eye injury.

            risk-warning

            Discoloration of contact lenses

            • Risk factors: Wearing soft contact lenses

              The preservative in Xdemvy (lotilaner), potassium sorbate, can change the color of your soft contact lenses. To prevent this from happening, make sure to remove your lenses before administering your drops. Wait 15 minutes before putting your lenses back in.

              dosage

              Xdemvy (lotilaner) dosage forms

              Typical dosing for Xdemvy (lotilaner)

              The typical dose is one drop in each eye twice daily (12 hours apart) for 6 weeks.

              alternatives

              What are alternatives to Xdemvy (lotilaner)?

              There are a number of medications that your doctor can prescribe in place of Xdemvy (lotilaner). Compare a few possible alternatives below.
              Xdemvy (lotilaner)
              Used for:
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              Hypochlorous acid
              Used for:
              $308.88 Lowest GoodRx priceView Prices
              images

              Xdemvy (lotilaner) images

              yellow - Xdemvy 0.25% Ophthalmic Solution
              This medicine is Yellow Eye Dropper.yellow - Xdemvy 0.25% Ophthalmic Solution

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              References

              Best studies we found

              Liu, J., et al. (2010). Pathogenic role of Demodex mites in blepharitis. Current Opinion in Allergy and Clinical Immunology.

              Tarsus Pharmaceuticals, Inc. (n.d.). Supporting your XDEMVY® prescription experience: Navigating XDEMVY access and savings.

              Tarsus Pharmaceuticals, Inc. (2023). FDA approves XDEMVY™ (lotilaner ophthalmic solution) 0.25% for the treatment of Demodex blepharitis. Globe Newswire.

              View All References (2)

              Tarsus Pharmaceuticals, Inc. (2023). Xdemvy- lotilaner ophthalmic solution solution/drops [package insert]. DailyMed.

              Yeu, E., et al. (2023). Lotilaner ophthalmic solution, 0.25%, for the treatment of Demodex blepharitis: Results of a prospective, randomized, vehicle-controlled, double-masked, pivotal trial (Saturn-1). Cornea.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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