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Major Depressive Disorder

Major depressive disorder is also known as clinical depression. It refers to having low mood, energy, and functioning for at least two weeks.

Symptoms of Depression: How Your Gender May Play a Role

In this video, learn how the genders can experience different symptoms of depression.

Sanjai Sinha, MD profile image

Reviewed by Sanjai Sinha, MD

Updated on September 13, 2025

When most people think of depression, they think of someone like Eeyore: sad, gloomy, and pessimistic. Some people with depression may be able to relate to Eeyore’s “symptoms,” but the truth is, depression can look very different from person to person — and even from gender to gender.

In general, women are more likely to experience the classic symptoms of depression, especially:

  • Chronic stress

  • Sadness

  • Sleeping too much or too little

  • Feelings of failure

  • And difficulty concentrating.

But men — particularly straight and cisgender men — may stray from these common symptoms. According to the National Institute of Mental Health, men who are depressed are more likely to exhibit the following signs:

  • Anger

  • Irritability

  • Aggressiveness

  • Loss of interest in hobbies and relationships

  • Morning fatigue

  • And impulsivity.

Because men have “atypical” symptoms of depression, many men (and their loved ones) do not easily recognize the behavioral and mood changes as depression. Not surprisingly, men are less likely to seek treatment for depression.

The disparity may stem from how young boys and girls are socialized. There are many factors and nuances, but here’s one obvious example: Little boys are often discouraged from crying or talking about their feelings. Many men grow up turning to anger instead of sadness when distressed, believing this is a more acceptable emotion.

On the other hand, girls are often allowed to cry and talk about feelings (and are often discouraged from being angry or violent). This also makes them more willing to recognize and admit their depression and seek help—often in the form of talk therapy.

LGBTQ individuals may face less pressure to stick to gender norms, but they experience depression at disproportionately high rates. (Learn more about the link between health and depression among LGBTQ individuals.)

Due to fear of discrimination, LGBTQ individuals with depression are less likely to seek treatment. Instead, they are more likely to turn to misusing alcohol, self-harming, or having suicidal thoughts. Sadly, LGBTQ youth are at least four times more likely to attempt suicide than heterosexual youth, according to the National Alliance on Mental Illness (NAMI) and the Centers for Disease Control and Prevention.

No matter your gender, your mental health matters. Feeling sad isn’t the only stipulation to get help for depression. If you notice changes to your mood and behaviors that are affecting your relationships, job, or general quality of life, you deserve help.

If you have depression and are experiencing thoughts of self-harm or suicide, call call the Suicide and Crisis Lifeline at 988.

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