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Understanding Your Role in Advancing Cancer Research

Common Myths About Clinical Trials for Cancer Treatment

It’s a myth that clinical trials are only for people with late-stage cancer.

Patricia Pinto-Garcia, MD, MPH profile image

Reviewed by Patricia Pinto-Garcia, MD, MPH

Updated on April 30, 2025

When you think about clinical trials, you may have certain ideas about what they’re like. However, there are a lot of myths about them, including their safety, how they work, and who is eligible. 

“It is important to have accurate information when deciding to participate in a clinical trial,” says June Y. Hou, MD, Gynecologic Oncologist at Columbia University’s Irving Medical Center. “Having accurate information will help you make a truly informed decision about weighing out the pros and cons.”

What are common myths about clinical trials?

Here are some of the most common myths you may have heard about clinical trials.

1. It’s a myth that clinical trials are unsafe.

Clinical trials are reviewed by organizations such as Institutional Review Boards. These committees ensure trials are safe and ethical before and during the trial. 

Also, you are closely monitored throughout the clinical trial. Many participants actually find the extra attention from their cancer care team to be a benefit of clinical trials.

2. It’s a myth that clinical trials are a “last resort” for treating cancer.

Clinical trials test treatments for cancers at every stage, not just late-stage cancer. You also don’t always need to have tried other treatments first to be eligible for a clinical trial. 

There are many available options, so it’s important to do your research if you think you’d like to find a clinical trial you’re eligible for.

3. It’s a myth that you can’t leave a clinical trial once you join.

You are never “stuck” once you’ve enrolled in a clinical trial. Your participation in the trial is voluntary. You can leave at any time if you are experiencing unexpected side effects, your cancer is progressing, or you simply want to.

4. It’s a myth that clinical trials only take place at larger hospitals.

There are many clinical trials available, not only at large hospitals, but also at cancer organizations, medical centers, local community hospitals, doctors’ offices, and veterans’ and military hospitals. You may even be able to participate in a clinical trial remotely.

If you do have questions about clinical trials, talk to your care team. If you’re already enrolled in one, Hou says to contact the cancer research team for answers to your questions.

References

ClinicalTrials.gov. (2024). Learn about studies. National Library of Medicine.

ECOG-ACRIN Cancer Research Group. (n.d.). Myths and facts about cancer clinical trials

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