Triferic (ferric pyrophosphate) is one of many injectable iron supplements available. However, it's the first and only FDA-approved medication for the replacement of iron in people with long-term kidney problems who are on hemodialysis.
Replacement of iron in adults with long-term kidney problems and on hemodialysis (dialysis through the blood)
Triferic (ferric pyrophosphate) is an iron supplement that helps replenish your body with this important mineral. Iron is an essential component of hemoglobin, a protein in your red blood cells that helps carry and deliver oxygen through your body.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Conveniently given during hemodialysis sessions
Can be given as either a separate IV infusion (Triferic AVNU) or mixed in with the dialysate solution (Triferic)
Works well to raise iron levels
Not used in people on peritoneal dialysis
Hasn't been studied in people receiving hemodialysis at home
Brand name only, which can be expensive
If you're prescribed Triferic AVNU, you'll receive it as an IV infusion for the length of the dialysis session, which is about 3 to 4 hours.
Mark your appointment(s) on your calendar to help you remember when to visit your dialysis center to receive hemodialysis and Triferic (ferric pyrophosphate). This will make sure you don't miss any doses or sessions.
Make sure you get your blood work done on time if your provider instructs you to. The results from these blood tests help your provider check your iron levels during Triferic (ferric pyrophosphate) treatment.
It's generally recommended to follow an iron-rich diet to help restore your iron levels. Foods containing iron include red meats (like beef or pork), dark leafy greens (like broccoli or kale), beans, and iron-enriched pasta and rice.
Triferic (ferric pyrophosphate) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: History of allergic reaction to another IV iron product
Triferic (ferric pyrophosphate) can cause serious allergic reactions, including anaphylaxis, which can be life-threatening. Symptoms of an allergic reaction can include rash, hives, shortness of breath, low blood pressure, fast heartbeat, dizziness, flushing, and fatigue. Your provider will monitor you for allergic reactions during and after your dialysis session. If you experience any symptoms of an allergic reaction, seek medical help right away.
Triferic AVNU: The typical dose is 6.75 mg given as an injection into the veins (intravenously, IV) during each hemodialysis session.
Triferic: Your provider will determine the correct dose for you. Triferic (ferric pyrophosphate) is mixed with the hemodialysis solution (dialysate) that you receive during your dialysis sessions.
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