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Toremifene

Toremifene Side Effects

Lauren Morton, PharmD, BCPSDaisy Chau, PharmD
Reviewed by Lauren Morton, PharmD, BCPS, Daisy Chau, PharmD
Last reviewed on December 19, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Hot flashes (35%)
  • Sweating (20%)
  • Nausea (14%)
  • Vaginal discharge (13%)
  • Cataracts (10%)
  • Dry eyes (9%)

Less Common Side Effects

  • Changes in vision
  • Dizziness
  • Swelling
  • Vomiting

Toremifene serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Abnormal heart rhythm: feel your heart beating, weakness, blurred vision, lightheadedness
  • Cancers of the uterus: abnormal vaginal bleeding, vaginal discharge, or pain or pressure in the area below your belly button (pelvis)
  • Blood clots in your veins or lungs: pain or swelling in your arms or legs, trouble breathing, chest pain, fast heartbeat

Source: DailyMed

The following Toremifene side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Anxiety

arm, back, or jaw pain

blurred vision

change in how much and how often you urinate

change in vaginal discharge

changes in skin color

changes in vision

changes in weight

chest pain, discomfort, tightness, or heaviness

confusion

constipation

cough

depression

dilated neck veins

dizziness, lightheadedness

dry mouth

fainting

fast, slow, or irregular heartbeat

inability to speak, incoherent speech

irregular breathing

loss of appetite

metallic taste in the tongue

muscle weakness

nausea

pain or discomfort in the arms, jaw, back, or neck

pain or feeling of pressure in the pelvis

pain, tenderness, or swelling of the foot or leg

seizures

severe or sudden headache

stomach pain

sweating

swelling of the face, fingers, feet, or lower legs

temporary blindness

tenderness, pain, swelling, warmth, skin discoloration, prominent superficial veins over the affected area

thirst

troubled breathing

unusual tiredness or weakness

vaginal bleeding

vomiting

weakness in the arm and or leg on one side of the body, sudden and severe

Incidence not known

Black, tarry stools

bleeding gums

blood in the urine or stools

chills

clay-colored stools

dark urine

fever

itching

painful or difficult urination

pinpoint red spots on the skin

rash

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

unpleasant breath odor

unusual bleeding or bruising

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blindness

decreased vision

dry eyes

feeling of warmth

redness of the face, neck, arms, and occasionally, the upper chest

sudden sweating

sweating

Less common

Bone pain

changes in vision

double vision

eye pain

tearing

Incidence not known

Blistering, crusting, irritation, itching, or reddening of the skin

cracked, dry, or scaly skin

depression

difficulty having a bowel movement

feeling of constant movement of self or surroundings

feeling unusually cold

hair loss

lack or loss of strength

partial or slight paralysis

sensation of spinning

shakiness in the legs, arms, hands, or feet

thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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