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HomeDrugsTadalafil Cialis

8 Essential Things to Know About Generic Cialis

Jennifer Gershman, PharmD, CPh, PACSStacia Woodcock, PharmD
Updated on November 1, 2024

Key takeaways:

  • Cialis (tadalafil) is an oral, prescription medication used to treat erectile dysfunction (ED). It also manages symptoms of an enlarged prostate.

  • Cialis and its generics have two possible dosing options. You can take the medication as needed before sex or consistently every day.

  • Cialis is available as a lower-cost generic. GoodRx can help you save over 90% off the average retail price at certain pharmacies.

Access savings on related medications

Cropped shot of someone taking an ED pill in bed.
grinvalds/iStock via Getty Images Plus

Cialis (tadalafil) is a popular prescription medication. It’s used to treat erectile dysfunction (ED) and an enlarged prostate. What’s more, Cialis generics have been available for several years, helping make this men’s health treatment more affordable.

Cialis is often compared to Viagra (sildenafil) since both are popular treatments for ED. But they come with different dosages and recommendations. They also have slightly different side effects.

If you have a new prescription for a Cialis generic, here are eight of the top things to keep in mind.

Save up to 97% on tadalafil cialis with GoodRxDifferent pharmacies offer different prices for the same medication. GoodRx helps find the best price for you.
Save up to 97% on tadalafil cialis with GoodRxDifferent pharmacies offer different prices for the same medication. GoodRx helps find the best price for you.

1. There are many manufacturers

Eli Lilly is the manufacturer of brand-name Cialis. But since Cialis went generic in 2018, many manufacturers have released their own generic versions. These Cialis generic companies currently include:

  • Accord Healthcare

  • Ajanta Pharma

  • Alembic Pharmaceuticals

  • Amneal Pharmaceuticals

  • Aurobindo Pharma

  • Cipla

  • Dr. Reddy’s Laboratories

  • Hetero Labs

  • Lupin

  • Macleods Pharmaceuticals

  • Prinston Pharmaceuticals

  • Qilu Pharmaceutical

  • Sun Pharmaceutical Industries

  • Sunshine Lake Pharma

  • Teva Pharmaceuticals

  • Torrent Pharmaceuticals

  • Umedica Laboratories

  • Unichem Laboratories

  • VKT Pharma

  • Zydus Pharmaceuticals

Good to know: The physical appearance of generic Cialis pills can vary among brands. You may notice this when you pick up your medication from the pharmacy. However, they contain the same active ingredient and work the same way. Reach out to your pharmacist with any questions about Cialis generic manufacturers.

2. There are ways to save on Cialis

There are ways to save on Cialis, which is available as both a brand-name and generic medication.

  • Save with GoodRx: GoodRx can help you save over 90% off the average retail price of the generic version. Generic Cialis's price at certain pharmacies is as low as $18.90 for 30 tablets with a free GoodRx discount. Brand-name Cialis may cost as little as $292.62, by comparison.

  • Save with patient assistance programs: If you’re uninsured or underinsured, you may be eligible for Cialis' patient assistance program, which offers the medication free of charge.

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Avg retail price
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GoodRx discount
$11.76
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3. You can take Cialis for ED in two ways

If you’re new to taking Cialis for ED, you may be looking for tips on how to maximize your treatment. Dosages are one important part of this.

Cialis and its generic equivalents are available as 2.5 mg, 5 mg, 10 mg, and 20 mg tablets. You can either take it “as needed” or once every day.

Taking Cialis as needed is the more common method. This is when you take a dose before you engage in sexual activity. A common Cialis dosage for ED is 10 mg by mouth 30 minutes before you plan to have sex. But medications work differently in everyone’s body, so your dose may be as low as 5 mg or as high as 20 mg.

However, taking Cialis every day allows you to have sex more spontaneously. The starting dosage is usually 2.5 mg by mouth once daily at around the same time each day. The dose can be raised to 5 mg once daily if needed.

Your prescriber and pharmacist can help you decide what dose and dosing schedule is best for you.

Good to know: Cialis interacts with several medications. This may impact your recommended Cialis dosage — especially if you’re taking a medication that could cause Cialis to stay in your body longer. One example is with the antifungal ketoconazole. For the “as needed” option, you shouldn’t take more than 10 mg of Cialis every 72 hours (3 days) if you’re also taking ketoconazole. If you’re taking Cialis daily along with ketoconazole, your prescriber will likely recommend sticking with a lower, 2.5 mg dose once daily.

4. Tadalafil is no different from brand-name Cialis

People regularly ask how well generic medications work compared to their brand-name counterparts.

In short, you shouldn’t expect any differences — other than a lower price tag.

GoodRx icon
  • Cialis tips and tricks: From how it works to possible side effects, pharmacists provide expert advice on maximizing your Cialis (tadalafil) prescription.

  • Cialis 101: Check out these answers to the most frequently asked questions about Cialis.

  • Avoiding interactions: Cialis interacts with certain medications, supplements, and foods. Learn from pharmacists about which interactions to be cautious of.

It’s important to remember that all medications go through a rigorous research and approval process before they hit the market. On top of that, the FDA has strict guidelines that make sure generic medications contain the same active ingredients and are just as effective and safe as their brand-name equivalents.

The biggest difference between brand-name Cialis and generic tadalafil is often the shape of the tablets. Cialis comes as a yellow, oval-shaped tablet. Tadalafil is also usually yellow, but it can be either oval- or circle-shaped depending on the manufacturer.

5. A different version of tadalafil also exists

Like Cialis, Adcirca is another brand-name version of tadalafil. Alyq is the generic version of Adcirca. Adcirca and Alyq are both prescription medications that treat pulmonary arterial hypertension, a type of high blood pressure in the arteries of the heart and lungs. Adcirca and Alyq come as 20 mg oral tablets.

Tadalafil also comes as an oral liquid under the brand-name Tadliq. This option comes in handy if you have difficulty swallowing pills. Tadliq is available as a 20 mg per 5 mL oral suspension.

6. Beware of counterfeit Cialis

Cialis is an in-demand medication, and at times has been the subject of counterfeit schemes and unauthorized compounding. In fact, Cialis counterfeits that contain unconfirmed ingredients have been reported in the past. Taking counterfeit medications can be dangerous.

You’re more likely to encounter a Cialis counterfeit while shopping online. If you buy your medications on the web, it’s important to do your research first. Here are some signs that an online pharmacy is safe:

  • A prescription from a healthcare professional is always required

  • A U.S. address and phone number are listed on website

  • A licensed pharmacist is available for questions

  • The pharmacy is licensed with a state board of pharmacy

  • The online pharmacy is certified with a VIPPS (Verified Internet Pharmacy Practice Sites) accreditation

Online providers like GoodRx Care that work with board-certified healthcare professionals can also be good options. Just be sure to reach out to your regular prescriber if you’re considering this route so they can stay on top of all of the medications you’re taking.

7. Tadalafil does have side effects

Cialis and tadalafil are effective ED treatment options. But there are some side effects you should be aware of before starting the medication, such as:

  • Headache

  • Upset stomach 

  • Back pain

  • Congestion

  • Flushing (redness in the face)

  • Muscle pain

  • Leg and arm pain

  • Diarrhea

According to a review of 16 studies comparing Cialis and Viagra, back and muscle pain were more common with Cialis. But flushing was more common with Viagra.

Cialis can also cause some rare but serious side effects. An erection lasting longer than 4 hours (priapism) is one example. There have also been reports of vision and hearing loss. If you experience any of these side effects, it’s important to seek medical care right away.

8. Cialis can treat more than erectile dysfunction

In addition to ED, Cialis and tadalafil are also approved to treat benign prostatic hyperplasia (BPH). This is a common health problem that affects the prostate as men get older. Cialis and tadalafil treat BPH by relaxing the muscle cells in the prostate so urine can flow more freely out of the bladder.

The recommended dose of Cialis for BPH is 5 mg once daily. This is also the recommended dose if you have both ED and BPH.

Frequently asked questions

Is Cialis available over the counter?

No, Cialis is a prescription-only medication. If you encounter any supplements claiming to contain tadalafil, the active ingredient in Cialis, you should avoid taking them. These products aren’t regulated by the FDA and could be counterfeit.

Is Cialis stronger than Viagra?

Cialis and Viagra are similarly effective ED medications. While it’s hard to definitively say if one is stronger than the other, Cialis may have the edge. Most people take a higher Viagra dosage to achieve similar effects for ED. Cialis also lasts longer in the body than Viagra.

When is the best time to take Cialis?

If you’re taking Cialis as needed, aim to take it at least 30 minutes before sex. However, if you’re taking Cialis on a daily basis, the time of day you take it is based on your personal preference. Morning, afternoon, or night — it’s up to you. The key is being consistent to maximize its benefits.

The bottom line

Brand-name and generic Cialis (tadalafil) is an effective treatment for erectile dysfunction (ED) and an enlarged prostate. You can take Cialis for ED as needed before sex or on a daily basis. Headache, congestion, and muscle pain are a few examples of common Cialis side effects. If you have an erection lasting longer than 4 hours, seek medical care right away. And to avoid counterfeit Cialis, make sure to only purchase it with a prescription from a trusted pharmacy.

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Why trust our experts?

Jennifer Gershman, PharmD, CPh, PACS
Jennifer Gershman, PharmD, is a licensed pharmacist in Florida. She has worked in the pharmacy industry for more than 15 years and is currently a medical writer.
Joshua Murdock, PharmD, BCBBS
Joshua Murdock, PharmD, BCBBS, is a licensed pharmacist in Arizona, Colorado, and Rhode Island. He has worked in the pharmacy industry for more than 10 years and currently serves as a pharmacy editor for GoodRx.
Stacia Woodcock, PharmD
Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.
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GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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