Therapeutic ClassificationsExchange Resin
This medicine is available only with your doctor's prescription.
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A nurse or other trained health professional will give you this medicine in a hospital. Sodium polystyrene sulfonate is given as a rectal enema.
Use this medicine at least 3 hours before or after taking oral medicines. If your stomach takes too long to empty food (gastroparesis), use this medicine 6 hours before or after taking oral medicines.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of sodium polystyrene sulfonate in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medicine in children are not expected.
This medicine should not be used in newborn infants who have reduced or slow bowel movements.
No information is available on the relationship of age to the effects of sodium polystyrene sulfonate in geriatric patients.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical ProblemsTOP
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Bowel blockage or
- Newborn infants who have slow bowel movements—Should not be used in patients with these conditions.
- Congestive heart failure, or
- Edema (fluid retention) or
- Heart rhythm problems (eg, arrhythmia, QT prolongation) or
- Hypertension (high blood pressure), severe or
- Hypocalcemia (low calcium in the blood) or
- Hypokalemia (low potassium in the blood)
- Hypomagnesemia (low magnesium in the blood)—Use with caution. May make these conditions worse.
- Hypovolemia (low blood volume) or
- Kidney disease—Use with caution. May cause side effects to become worse.
It is very important that your doctor check you closely to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.
Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have the following symptoms: confusion, dry mouth, increased thirst, irregular heartbeat, irritability, muscle cramps, nausea or vomiting, or shortness of breath.
This medicine may cause a serious stomach or bowel problem, called intestinal necrosis. This is more likely to occur if you have a history of bowel disease, bowel surgery, low blood volume, kidney problems or if you take sorbitol together with this medicine. Tell your doctor right away if you or your child have severe constipation, severe stomach pain, bloody, black, or tarry stools, or vomit blood or a material that looks like coffee grounds.
This medicine may cause lung or breathing problems (eg, bronchitis, bronchopneumonia) when you inhale its powder form. It may also increase your risk of having aspiration. Take this medicine in an upright position to prevent this. Talk to your doctor if you have questions.
If you are taking aluminum or magnesium-containing antacids or laxatives, tell your doctor before using sodium polystyrene sulfonate. These medicines may keep sodium polystyrene sulfonate from working properly and may cause serious side effects.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.