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Simcor

niacin and simvastatin
Used for High Cholesterol
Used for High Cholesterol

Simcor (niacin / simvastatin) is a combination medication used to treat high cholesterol and triglycerides (fats). This medication has been discontinued and is no longer available in the United States.

Reviewed by:
reviewer
Sarah Lobello Pearson, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on June 5, 2022
BasicsFAQsInteractionsAlternativesPricesMedicare
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What is Simcor (niacin / simvastatin)?

What is Simcor (niacin / simvastatin) used for?

  • High cholesterol

  • High triglycerides

How Simcor (niacin / simvastatin) works

Drug Facts

Common BrandsSimcor (brand no longer available)
Drug ClassAntilipemic / Statin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Simcor (niacin / simvastatin)

What is Simcor (niacin / simvastatin)?
Simcor (niacin / simvastatin) is a combination of two medications: niacin extended release (ER) and simvastatin. Niacin works by affecting certain key pathways responsible for making cholesterol and triglycerides in the body. Simvastatin works by blocking cholesterol production in the liver. By working together, the two medications help lower low-density lipoprotein (LDL, or "bad" cholesterol) and triglycerides.
Is Simcor (niacin / simvastatin) still available?
No, Simcor (niacin / simvastatin) has been discontinued and is no longer available in the United States.
Why was Simcor (niacin / simvastatin) discontinued?
Simcor (niacin / simvastatin) was discontinued because the FDA determined that adding niacin ER to simvastatin therapy didn't lower the risk of heart-related events (e.g., heart attack, stroke) any more than simvastatin alone. The manufacturer of the combination medication (AbbVie) then voluntarily withdrew it from the market.
What can I use instead of Simcor (niacin / simvastatin)?
Both of the active ingredients in Simcor (niacin / simvastatin) are still available as single-ingredient medications: simvastatin (Zocor) and niacin ER. These medications can be used to lower cholesterol and triglycerides. There are also many other medications available for lowering cholesterol. Talk to your provider about what the best treatment option might be for you.
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interactions

Interactions between Simcor (niacin / simvastatin) and other drugs

Simcor (niacin / simvastatin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Simcor (niacin / simvastatin). Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

alternatives

What are alternatives to Simcor (niacin / simvastatin)?

There are a number of medications that your doctor can prescribe in place of Simcor (niacin / simvastatin). Compare a few possible alternatives below.
Simcor (niacin / simvastatin)
Used for:

  • High cholesterol

  • High triglycerides

View Prices
Simvastatin (Zocor)
Used for:
$12.60 Lowest GoodRx priceView Prices
Niacin ER
Used for:

  • High cholesterol and high triglycerides

  • Lower risk of repeat heart attack in people with a history of heart attack and high cholesterol

  • Slow plaque buildup in the arteries of people with a history of coronary artery disease (CAD) and high cholesterol (as an add-on medication)

  • Severely high triglycerides in people who are at risk of pancreatitis (as an add-on medication)

$27.30 Lowest GoodRx priceView Prices

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