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Rezzayo

rezafungin
Used for Candidiasis
Used for Candidiasis

Rezzayo (rezafungin) is an injectable medication used to treat serious infections caused by a fungus called Candida. It's typically injected into the veins by a trained healthcare provider once a week. Some of the most common side effects of Rezzayo (rezafungin) include diarrhea, nausea, vomiting, and stomach pain. This medication can also cause your skin to become more sensitive to sunlight.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Connie Zheng, PharmD
Last reviewed on August 20, 2023
BasicsFAQsAlternativesReferencesPricesMedicare
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What is Rezzayo (rezafungin)?

What is Rezzayo (rezafungin) used for?

  • Serious fungal infection caused by Candida in adults

How Rezzayo (rezafungin) works

Rezzayo (rezafungin) is an antifungal. It kills the fungus by preventing it from making its protective outer covering.

Drug Facts

Common BrandsRezzayo
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Rezzayo (rezafungin)

What is Rezzayo (rezafungin) used for?
Rezzayo (rezafungin) is used to treat adults with serious infections caused by a fungus called Candida, including infections in the blood and certain other parts of the body. It's typically used when there are limited or no other treatment options.
How is Rezzayo (rezafungin) given?
Rezzayo (rezafungin) is injected into the veins (IV) by a trained healthcare provider. The typical dose is 400 mg IV, followed by 200 mg IV once weekly. Each infusion takes about 1 hour.
How long will I receive Rezzayo (rezafungin)?
Your provider will decide how long you should receive Rezzayo (rezafungin) based on things like how serious your infection is, if you're having side effects, and how you're responding to the medication. In studies, people typically needed 2 to 4 weekly doses of Rezzayo (rezafungin).
What are the common side effects of Rezzayo (rezafungin)?
Some of the most common side effects of Rezzayo (rezafungin) include fever, diarrhea, nausea, vomiting, and stomach pain. Rezzayo (rezafungin) can also cause electrolyte changes, such as low potassium, low magnesium, and low phosphate levels in your blood. It can also cause low red blood cells (anemia). Let your provider know if you feel more tired than usual or notice pale skin, since these could be signs of anemia.
Are infusion reactions possible with Rezzayo (rezafungin)?
Yes. Some people have reported infusion-related reactions from Rezzayo (rezafungin), such as feeling warm all of a sudden, hives, nausea, and chest tightness. If you experience any of these symptoms, let your care team know right away. They can slow or stop the infusion if necessary.
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alternatives

What are alternatives to Rezzayo (rezafungin)?

There are a number of medications that your doctor can prescribe in place of Rezzayo (rezafungin). Compare a few possible alternatives below.
Rezzayo (rezafungin)
Used for:

  • Serious fungal infection caused by Candida in adults

View Prices
Micafungin (Mycamine)
Used for:
View Prices
Caspofungin (Cancidas)
Used for:

  • Fungal infections in people with a fever and a low number of white blood cells

  • Candidemia (a fungal infection in your blood) and other infections caused by Candida

  • Candidiasis of the esophagus (thrush in the esophagus)

  • Invasive aspergillosis (a serious fungal infection affecting multiple areas of the body)

$975.65 Lowest GoodRx priceView Prices

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References

Best studies we found

Centers for Disease Control and Prevention. (2020). Invasive candidiasis.

Garcia-Effron, G. (2020). Rezafungin-Mechanisms of action, susceptibility and resistance: similarities and differences with the other echinocandins. Journal of Fungi.

Melinta Therapeutics, LLC. (2023). Rezzayo- rezefungin injection, powder, lyophilized, for solution [package insert]. DailyMed.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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