Pseudobulbar Affect
What is Pseudobulbar Affect?
Pseudobulbar Affect (PBA) is a condition that is characterized by sudden, uncontrollable episodes of laughing or crying triggered by emotionally trivial or neutral stimuli. PBA is frequently caused by another neurological disorder or brain injury.
Treatments for Pseudobulbar Affect include taking medication and cognitive behavioral therapy. Common drug classes used to treat PBA include tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), and NMDA receptor antagonist/antiarrhythmic combinations.
Popular Pseudobulbar Affect Drugs
Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.
Pseudobulbar Affect: Drug Classes
Pseudobulbar Affect drugs are grouped into the following classes based on how they work:
NMDA receptor antagonist / antiarrhythmic combinations are used to treat multiple sclerosis and ALS. They work by controlling involuntary laughing or crying which is known as pseudobulbar affect (PBA).
Learn about NMDA Receptor Antagonist / Antiarrhythmic Combinations