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Praziquantel

Praziquantel Side Effects

Ally Tsai, PharmDRobert Chad Hakim, PharmD, BCCCP
Reviewed by Ally Tsai, PharmD, Robert Chad Hakim, PharmD, BCCCP
Last reviewed on May 14, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Feeling tired
  • Headache
  • Dizziness
  • Stomach discomfort
  • Nausea
  • Itchiness
  • Drowsiness
  • Fever

Less Common Side Effects

  • Vertigo (feeling like your surroundings are spinning)
  • Ringing in the ear
  • Changes in vision
  • Vomiting
  • Loss of appetite
  • Muscle pain
  • Shortness of breath
  • Wheezing
  • Itching
  • Rash

Praziquantel serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Irregular heart rhythm: heart flutter, slow or fast heartbeat, extra beats, lightheadedness, dizziness, trouble breathing, chest pain
  • Seizures
  • Brain or nervous system problems: severe headaches, confusion, not paying attention to people and your surroundings, fainting, personality changes
When do Praziquantel possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Feeling tired
Stomach pain
Nausea
Diarrhea
Itching

Source: DailyMed

The following Praziquantel side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

bloody diarrhea

blurred or loss of vision

chest pain or discomfort

chills

cough

dark urine

diarrhea

difficulty swallowing

difficulty with moving

disturbed color perception

dizziness

double vision

fainting

fast, slow, or irregular heartbeat

fever

general feeling of discomfort or illness

general tiredness and weakness

halos around lights

hives, itching, skin rash

joint pain, stiffness, or swelling

light-colored stools

lightheadedness, dizziness, or fainting

muscle pains, cramps, or stiffness

nausea

night blindness

overbright appearance of lights

painful or difficult urination

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

redness of the skin

severe abdominal or stomach pain

seizures

sleepiness or unusual drowsiness

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach discomfort with or without nausea

stomach pain

sweating

swelling of the eyelids, face, lips, hands, or feet

swollen glands

thickening of bronchial secretions

tightness in the chest

tremor

troubled breathing

tunnel vision

unusual bleeding or bruising

unusual tiredness or weakness

upper right abdominal pain

vomiting

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Change in walking and balance

clumsiness or unsteadiness

continuing ringing or buzzing or other unexplained noise in the ears

dizziness or lightheadedness

feeling of constant movement of self or surroundings

headache

hearing loss

lack or loss of strength

loss of appetite

sensation of spinning

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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