Skip to main content

Photrexa

riboflavin 5'-phosphate
Used for Visual Distortion
Used for Visual Distortion

Photrexa is an eye drop used with a special lamp called the KXL System to treat certain eye conditions that involve thinning of the cornea. It's applied to the eye by a trained healthcare provider at their office before and during treatment with the KXL System. Since this medication is brand only, it can be expensive.

Last reviewed on May 8, 2022
basics-icon

What is Photrexa?

How Photrexa works

Drug Facts

Common BrandsPhotrexa
Drug ClassOphthalmic agent
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Photrexa

What is Photrexa?
Photrexa is an eye drop that's used with a machine called the KXL System to treat 2 eye conditions - progressive keratoconus and corneal ectasia as a result of surgery. These conditions can happen when a part of your eye called the cornea becomes too thin and can result in vision problems. Photrexa contains riboflavin, also known as vitamin B2, and is a photosensitizer. This means that it absorbs ultraviolet (UV) light from the KXL System and produces a chemical change in the eye that helps cross-link collagen (a protein that makes the cornea more stiff) in the eye to strengthen the cornea again and prevent your vision from getting worse.
How is Photrexa given?
Photrexa is an eye drop given by a healthcare provider at their office to prepare your eye for treatment with the KXL System. First, your provider will apply some topical numbing medication to your eye and prep the area. The typical dose is 1 drop of Photrexa into the affected eye(s) every 2 minutes for 30 minutes. After 30 minutes, your provider will check your eye(s) under a special lamp called a slit lamp. Your provider might need to repeat giving you Photrexa drops in your eye(s) until they see a yellow flare under the lamp. Then, they'll use another lamp called the KXL System for 30 minutes while applying 1 drop onto the affected eye(s) every 2 minutes.
What should I know after I get treatment with Photrexa?
Before your procedure, your provider will give you instructions about what to do when you're ready to go home after your Photrexa treatment. Don't rub your eye(s) for the first 5 days after treatment, since your eye(s) will need some time to heal properly. It's normal for your eye(s) to be sensitive to light or feel like there is something inside, which might be uncomfortable. You can wear sunglasses to help with the light sensitivity. Contact your provider if you experience severe pain in your eye(s), any vision changes, or if the bandage contact lens that was placed on your eye(s) falls out. Don't try to put the bandage contact lens back in yourself.
What are the side effects of Photrexa?
Some common side effects of Photrexa are hazy vision, eye pain, blurry vision, and sensitivity to light. While some discomfort after your procedure is normal, contact your provider if you experience severe pain or vision changes.
Can Photrexa be used in children?
There haven't been enough studies to know if Photrexa is safe or works in children under 14 years old. Discuss alternative treatment options with your child's provider.
GoodRxEducationalIcon

How to save using GoodRx

Compare Prices
1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
Select your free coupon
2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
Show coupon to your pharmacist
3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
Get free couponLearn more

Get savings updates for Photrexa

Receive price alerts, news, and other messages from GoodRx about Photrexa and other healthcare topics and relevant savings offers.

By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men’s health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.