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Paricalcitol

Paricalcitol Side Effects

Ashley Wong, PharmDAllison Gourley, PharmD
Reviewed by Ashley Wong, PharmD, Allison Gourley, PharmD
Last reviewed on September 8, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (5–13%)
  • Diarrhea (7–12%)
  • Common cold (8%)
  • Vomiting (5–8%)
  • High blood pressure (7%)
  • Swelling (6–7%)
  • Dizziness (5–7%)

Less Common Side Effects

  • Runny nose
  • Infections
  • Low blood pressure
  • Chills
  • Trouble sleeping
  • Feeling like you're spinning (vertigo)
  • Headache
  • Rash
  • High fluid in your blood
  • Bleeding in your stomach
  • Stomach infection
  • Constipation
  • Urge to urinate
  • Flu
  • Arthritis or join pain, arthritis
  • Weakness
  • Pink eye
  • Asthma
  • Lung infection (pneumonia)
  • Fever

Paricalcitol serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions: itching, hives, trouble breathing, swelling of your face, lips, tongue, or throat
  • High calcium levels: tiredness, trouble thinking clearly, loss of appetite, nausea, vomiting, constipation, more thirst, more urination, weight loss

Source: DailyMed

The following Paricalcitol side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision

cough or hoarseness

difficulty with swallowing

dizziness

fever or chills

headache

hives

itching

lower back or side pain

nervousness

pain

painful or difficult urination

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

shortness of breath

skin rash

slow or fast heartbeat

swelling

tightness in the chest

unusual tiredness or weakness

Less common

Abdominal or stomach pain

abnormal growth filled with fluid or semisolid material

ammonia-like breath odor

anxiety

bladder pain

bloating or swelling of the face, arms, hands, lower legs, or feet

bloody or cloudy urine

burning, tingling, numbness or pain in the hands, arms, feet, or legs

chest pain or discomfort

cold sweats

coma

confusion

convulsions

cool, pale skin

decreased urine

depression

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

drowsiness

dry mouth

fainting

frequent urge to urinate

general feeling of discomfort or illness

increase in heart rate

increased hunger

increased thirst

irregular heartbeat

joint pain

lightheadedness

loss of appetite

muscle aches and pains

nausea or vomiting

nightmares

numbness or tingling in the hands, feet, or lips

pain or discomfort in the arms, jaw, back, or neck

rapid breathing

rapid weight gain

runny nose

sensation of pins and needles

shakiness

shivering

slurred speech

sneezing

sore throat

stabbing pain

sunken eyes

sweating

thirst

trouble sleeping

troubled breathing

unusual weight gain or loss

weight loss

wrinkled skin

Incidence not known

Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

slow or irregular breathing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Abdominal or stomach cramps

constipation

depression

high urine levels of calcium

incoherent speech

increased urination

metallic taste

muscle cramps in the hands, arms, feet, legs, or face

muscle weakness

tremor

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Acid or sour stomach

back pain

belching

bloody nose

bruising

change in vision

cough producing mucus

difficulty with moving

feeling of constant movement of self or surroundings

heartburn

impaired vision

indigestion

lack or loss of strength

large, flat, blue, or purplish patches in the skin

leg cramps

muscle pain or stiffness

pain or tenderness around the eyes and cheekbones

pain, swelling, or redness in the joints

sensation of spinning

sores on the skin

stomach discomfort, upset, or pain

stuffy nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Ashley Wong, PharmD, is a licensed pharmacist in California. She has over 6 years of experience providing drug information.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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