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Neomycin/Polymyxin B/Hydrocortisone Coupon - Neomycin/Polymyxin B/Hydrocortisone 10ml ear dropper

neomycin / polymyxin b / hydrocortisone

Generic Cortisporin
Used for Bacterial Infection, Ear Infection, Eye Infection, Eye Inflammation

Cortisporin eye drop is used to treat and relieve signs and symptoms of a bacterial eye infection in adults. It contains two antibiotics (neomycin and polymyxin B) and a steroid (hydrocortisone). The usual dosage is 1 to 2 drops in the affected eye(s) every 3 to 4 hours. Side effects include itchy, swollen, or red eyes. This medication is only available as a lower-cost generic.

Cortisporin is also available as an ear drop.

Reviewed by:Last reviewed on September 12, 2024
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What is Cortisporin eye drop?

What is Cortisporin eye drop used for?

  • Eye inflammation caused by or at risk of a bacterial infection

How Cortisporin eye drop works

Cortisporin eye drop is a combination of three medications:

  • Neomycin is an antibiotic. It kills bacteria by preventing them from making proteins that they need to survive.
  • Polymyxin B is another antibiotic. It kills bacteria by destroying the bacteria's protective covering.
  • Hydrocortisone is a corticosteroid. When used in the eye, it helps lower inflammation, which includes symptoms like pain, redness, and swelling.

Drug facts

Common BrandsCortisporin(brand name no longer available)
Drug ClassAntibiotic / Corticosteroid
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Cortisporin eye drop

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Eye irritation

Less Common Side Effects

  • Slowed eye healing

Cortisporin eye drop serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: swollen eyelids, red or itchy eyes, shortness of breath
  • High eye pressure: blind spots in side vision, vision loss, eye pain

Source: DailyMed

The following Cortisporin eye drop side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Itching, skin rash, redness, swelling, or other signs of irritation in or around the ear not present before the use of this medicine

Rare

Stinging and burning feeling in the middle ear

Incidence not known

Blood in the urine

change in the frequency of urination or amount of urine

difficulty in breathing

dizziness

drowsiness

feeling of fullness in the ears

increased thirst

loss of appetite

loss of balance

loss of hearing

nausea

ringing or buzzing in the ears

swelling of the feet or lower legs

trouble in hearing

vomiting

weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Cough

difficulty swallowing

fast heartbeat

hives, itching, skin rash

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

tightness in the chest

unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Avg retail price
$104.99(Save 70.63%)
GoodRx discount
$30.84
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Pros and cons of Cortisporin eye drop

Pros

  • Treats eye inflammation and bacterial infection at the same time
  • Conveniently combines three medications into one eye drop
  • Generally has few side effects
  • Available as a lower-cost generic medication

Cons

  • Has a risk of getting other eye infections
  • Needs to be used multiple times a day
  • Doesn't treat fungal or viral infections
  • Eye exam needed after 10 days of use to check eye pressure
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Pharmacist tips for Cortisporin eye drop

pharmacist
  • Since Cortisporin eye drop is an eye suspension, shake it before using it to mix the medication well. This will make sure the medication hasn’t settled at the bottom of the bottle.
  • Don't let the tip of the Cortisporin eye drop bottle touch the eye, eyelid, fingers, or other surfaces. Doing so can contaminate the medication and cause serious harm to the eye, such as vision loss.
  • If you need to use another eye drop with Cortisporin eye drop in the same eye, wait at least 5 minutes so the second eye drop doesn't rinse off the first one.
  • Use Cortisporin eye drop as directed by your prescriber. Don't stop using before you complete treatment, even if you feel better. If you stop using Cortisporin eye drop too soon, your infection might come back stronger.
  • If you need more than 2 bottles of Cortisporin eye drop or if you need to use this medication more than 10 days, your prescriber or eye specialist will need to check your eyes to make sure this medication is appropriate and safe for you.
  • Talk with your prescriber if your eye inflammation gets worse or lasts more than 2 days. They can check your eyes to make sure Cortisporin eye drop is working as it should.

How to use Cortisporin eye drop:

  • Pull down your lower eyelid with one hand and hold the bottle upside down above your eye. Then squeeze the number of drops needed for your dose.
  • Close your eye, then press down with your finger on the inner corner of your eye near your nose for one minute to keep the medication in place and prevent it from leaking.
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Risks and warnings for Cortisporin eye drop

Cortisporin eye drop can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

High eye pressure

  • Risk factors: Using Cortisporin eye drop for more than 10 days | History of glaucoma

Using topical steroid medications like Cortisporin eye drop long term can cause high eye pressure that can damage the eye and cause vision loss. If you have glaucoma or high eye pressure, talk with your prescriber about the benefits and risks of using Cortisporin eye drop. Your prescriber will check your eye pressure to make sure it's safe for you, especially if you're using this medication for more than 10 days. Talk with your care team immediately if you experience signs and symptoms of high eye pressure, such as eye pain, blurry vision, or blind spots in your side vision.

Other eye infections

  • Risk factors: Using Cortisporin eye drop for more than 10 days

Using Cortisporin eye drop long term can raise the risk of other eye infections, such as fungal or viral eye infections. Don't use Cortisporin eye drop if you have a viral eye infection because it can make your infection worse. Talk with your prescriber if you have eye pain or redness, blurry vision, light sensitivity, or watery discharge from your eye. These can be signs and symptoms of a viral or fungal eye infection.

New eye problems

  • Risk factors: History of cataract

Using Cortisporin eye drop might cause your cornea (the "whites" of the eye) to thin. Sometimes, this can lead to eye damage. In addition, Cortisporin eye drop can cause cataracts to form. If you have vision loss, blurry vision, eye pain, or your eye is more watery than usual, please seek medical attention right away.

Using Cortisporin eye drop after a cataract surgery might also slow down the healing process and raise the risk of fluid buildup in the eye. If you’ve just had cataract surgery and are experiencing eye problems, talk with your eye surgeon right away.

Allergic reaction to topical antibiotics

Tell your prescriber before using Cortisporin eye drop if you have a history of allergy to antibiotics, such as gentamicin (Gentak), streptomycin, and paromomycin. Watch out for signs and symptoms of allergic reactions, such as swollen eyelids or red or itchy eyes. Stop using Cortisporin eye drop and tell your prescriber if you have these signs and symptoms. Oftentimes, these reactions go away on their own once you stop the medication.

You might also be allergic to Cortisporin eye drop if your infection symptoms don't get better after a while. Speak with your prescriber if your eye doesn't improve after a couple days of using this medication.

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Cortisporin eye drop dosage

The average cost for 1 ear dropper of 10ml of Cortisporin eye drop is $30.84 with a free GoodRx coupon. This is 70.63% off the average retail price of $104.99.
ear dropperEar dropper
DosageQuantityPrice as low asPrice per unit
10ml1 ear dropper$30.84$30.84
eye dropperEye dropper
DosageQuantityPrice as low asPrice per unit
7.5ml1 eye dropper$51.71$51.71

Typical dosage for Cortisporin eye drop

The typical starting dose is 1 or 2 drops in the affected eye(s) every 3 or 4 hours. Depending on how serious your condition is, your prescriber might recommend using the eye drops more often.

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Interactions between Cortisporin eye drop and other drugs

Cortisporin eye drop may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Cortisporin eye drop. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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How much does Cortisporin eye drop cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Cortisporin eye drop (generic)
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$30.84

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Cortisporin eye drop contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Cortisporin eye drop will not be safe for you to take.

  • Viral eye infections
  • Mycobacterial or fungal eye infections
alternatives-icon

What are alternatives to Cortisporin eye drop?

There are a number of medications that your doctor can prescribe in place of Cortisporin eye drop. Compare a few possible alternatives below.
Cortisporin eye drop
Used for:
  • Eye inflammation caused by or at risk of a bacterial infection
$30.84Lowest GoodRx priceView prices
Used for:
  • Bacterial eye infection with inflammation
  • Prevent bacterial eye infection with inflammation
$20.81Lowest GoodRx priceView prices
Used for:
  • Eye inflammation from a bacterial infection in the eye
  • Eye inflammation when there's a risk for a bacterial infection in the eye
$11.98Lowest GoodRx priceView prices
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News about Cortisporin eye drop

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Cortisporin eye drop images

This medicine is Colorless Ear Dropper.
white - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension
This medicine is White Ear Dropper.white - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension
colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Solution
This medicine is Colorless Ear Dropper.colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Solution
colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension
This medicine is Colorless Ear Dropper.colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension
colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Solution
This medicine is Colorless Ear Dropper.colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Solution
colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension
This medicine is Colorless Ear Dropper.colorless - Neomycin Sulfate/Polymyxin B Sulfate/Hydrocortisone Otic Suspension

References

Best studies we found

American Academy of Ophthalmology. (2016). Sclera.

Centers for Disease Control and Prevention. (2024). Fungal eye infections basics.

Fung, A. T., et al. (2019). Local delivery of corticosteroids in clinical ophthalmology: A review. Clinical & Experimental Ophthalmology.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.