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Mitosol

mitomycin
Used for Glaucoma

Mitosol (mitomycin) is a medication used during glaucoma surgery in adults to help the prevent scarring and improve success of the procedure. It's applied to the surgery site by a healthcare provider in the operating room.

Reviewed by:
reviewerKristianne Hannemann, PharmD
reviewerConnie Zheng, PharmD
Last reviewed on May 16, 2022
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What is Mitosol (mitomycin)?

What is Mitosol (mitomycin) used for?

  • To prevent scarring from glaucoma surgery

Drug facts

Common BrandsMitosol
Drug ClassOphthalmic agent
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Common questions about Mitosol (mitomycin)

Mitosol (mitomycin) is a solution that's applied to the eye in glaucoma filtration surgery, also known as a trabeculectomy procedure. The purpose of this procedure is to lower the pressure inside the eye by making a small hole in the eye to drain out the extra fluid. Mitosol (mitomycin) is used in this surgery to prevent scarring.

Mitosol (mitomycin) belongs to a group of medications called antimetabolites. It prevents scars from forming around the surgery site by stopping the growth of cells that form scar tissue.

Your provider will prepare Mitosol (mitomycin) and apply it onto the treatment area with sponges for 2 minutes.

No. Mitosol (mitomycin) can only be applied by a trained healthcare provider during glaucoma filtration surgery. It can cause serious side effects if used incorrectly.

Some side effects of Mitosol (mitomycin) include low eye pressure, eye infection, inflammation of eye fluids, and cataract (a cloudy area in the lens of the eye). If you notice any changes in your vision, pain, swelling, or redness in your eye, contact your provider.

Mitosol (mitomycin) hasn't been studied in pregnancy or breastfeeding. Based on animal studies, it can cause harm to unbabies and shouldn't be used during pregnancy. Because of the potential harm it can cause to breastfed babies, it's also not recommended during nursing. Females who are nursing are recommended to stop breastfeeding for 1 week after treatment with Mitosol (mitomycin). Speak with your provider if you've questions or concerns.

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Mitosol (mitomycin) dosage

Typical dosage for Mitosol (mitomycin)

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Interactions between Mitosol (mitomycin) and other drugs

Mitosol (mitomycin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Mitosol (mitomycin). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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