Methylene Blue may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Methylene Blue. Please note that only the generic name of each medication is listed below.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Amitriptyline
- Amoxapine
- Amphetamine
- Atomoxetine
- Benzphetamine
- Bupropion
- Carbamazepine
- Carbidopa
- Carbinoxamine
- Citalopram
- Clomipramine
- Codeine
- Cyclobenzaprine
- Desipramine
- Desvenlafaxine
- Deutetrabenazine
- Dexmethylphenidate
- Dextroamphetamine
- Doxepin
- Doxylamine
- Duloxetine
- Entacapone
- Escitalopram
- Fenfluramine
- Fluoxetine
- Fluvoxamine
- Hydroxytryptophan
- Imipramine
- Isocarboxazid
- Levodopa
- Levomilnacipran
- Linezolid
- Lisdexamfetamine
- Maprotiline
- Meperidine
- Methamphetamine
- Methylphenidate
- Milnacipran
- Mirtazapine
- Nortriptyline
- Ozanimod
- Paroxetine
- Phenelzine
- Phentermine
- Protriptyline
- Pseudoephedrine
- Rizatriptan
- Safinamide
- Selegiline
- Serdexmethylphenidate
- Sertraline
- Solriamfetol
- Sumatriptan
- Tapentadol
- Tramadol
- Tranylcypromine
- Trazodone
- Trimipramine
- Tryptophan
- Venlafaxine
- Vilazodone
- Viloxazine
- Vortioxetine
- Zolmitriptan
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Alfentanil
- Almotriptan
- Alprazolam
- Amineptine
- Amitriptylinoxide
- Atropine
- Benzhydrocodone
- Bromazepam
- Brompheniramine
- Buprenorphine
- Buspirone
- Butorphanol
- Calcium Oxybate
- Cannabidiol
- Cetirizine
- Chlorpheniramine
- Clobazam
- Cocaine
- Dextromethorphan
- Dibenzepin
- Difenoxin
- Dihydrocodeine
- Diphenoxylate
- Dolasetron
- Eletriptan
- Epinephrine
- Esketamine
- Fentanyl
- Flibanserin
- Frovatriptan
- Furazolidone
- Gabapentin
- Gabapentin Enacarbil
- Granisetron
- Hydrocodone
- Hydromorphone
- Iobenguane I 123
- Iobenguane I 131
- Iproniazid
- Ketamine
- Lasmiditan
- Lemborexant
- Levocetirizine
- Levorphanol
- Lithium
- Lofepramine
- Lofexidine
- Lorcaserin
- Loxapine
- Magnesium Oxybate
- Melitracen
- Metaxalone
- Methadone
- Metoclopramide
- Midodrine
- Moclobemide
- Morphine
- Morphine Sulfate Liposome
- Nalbuphine
- Naratriptan
- Nefazodone
- Nialamide
- Norepinephrine
- Ondansetron
- Opipramol
- Oxycodone
- Oxymetazoline
- Oxymorphone
- Palonosetron
- Pentazocine
- Periciazine
- Potassium Oxybate
- Pregabalin
- Procarbazine
- Rasagiline
- Remifentanil
- Remimazolam
- Sibutramine
- Sodium Oxybate
- St John's Wort
- Sufentanil
- Tianeptine
- Valbenazine
- Ziprasidone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acarbose
- Chlorpropamide
- Glimepiride
- Glipizide
- Glyburide
- Insulin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Metformin
- Nateglinide
- Repaglinide
- Tolazamide
- Tolbutamide
