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Methyldopa

Methyldopa Side Effects

Kristianne Hannemann, PharmDDaisy Chau, PharmD
Reviewed by Kristianne Hannemann, PharmD, Daisy Chau, PharmD
Last reviewed on October 1, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Temporary sleepiness
  • Temporary dizziness
  • Temporary weakness
  • Temporary headaches
  • Dry mouth
  • Trouble getting or maintaining an erection

Less Common Side Effects

  • Nausea
  • Vomiting
  • Gas
  • Swelling
  • Depression
  • "Pins and needles" sensation
  • Muscle pain
  • Lowered sex drive
  • Weight gain

Methyldopa serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Breakdown of red blood cells: tiredness, dizziness, weakness, headache, chills, paleness, fainting
  • Liver damage: severe stomach pain, nausea, vomiting, pale stools, dark urine, severe bloating in the stomach area, yellowing of the skin or whites of the eyes

Source: DailyMed

The following Methyldopa side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Fever, shortly after starting to take this medicine

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Swelling of feet or lower legs

Less common

Mental depression or anxiety

nightmares or unusually vivid dreams

Rare

Dark or amber urine

diarrhea or stomach cramps (severe or continuing)

fever, chills, troubled breathing, and fast heartbeat

general feeling of discomfort or illness or weakness

joint pain

pale stools

skin rash or itching

stomach pain (severe) with nausea and vomiting

tiredness or weakness after having taken this medicine for several weeks (continuing)

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Drowsiness

dryness of mouth

headache

Less common

Decreased sexual ability or interest in sex

diarrhea

dizziness or lightheadedness when getting up from a lying or sitting position

nausea or vomiting

numbness, tingling, pain, or weakness in hands or feet

slow heartbeat

stuffy nose

swelling of breasts or unusual milk production

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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